TY  - BOOK
AU  - Castillo,  Aileen  K., M.D.
TI  - A Case Report on Multiple System Atrophy : The Hot Cross Bun Sign 
AV  - RESRAD20170002 
PY  - 2017///
CY  - QUEZON CITY
PB  - FEU-NRMF
N1  - research
N2  - ABSTRACT: Multiple System Atrophy (MSA) is a rare sporadic progressive neurologic disorder affecting the striatonigral, olivopontocerebellum and central autonomic degeneration with 0.6 new MSA cases arising per 100,000 persons per year; a prevalence of 4-5 cases per 100,000 persons. Although diagnosed clinically, current researches have played a role in the diagnosis of the aforementioned syndrome, documenting the presence of the hot cross bun sign in T2 weighted MR imaging. F.G. is a 48 year old male parking attendant presented with an insidious onset of gradual progressive staggering broad based gait, intention tremors, and slowness of activities for a year. It was associated with postural dizziness and increased frequency of urination. T2 weighted imaging demonstrated the hot cross bun sign and atrophy of the brainstem, cerebellum and/or middle cerebellar peduncle.Early clinical course and infratentorial atrophy makes differentiating MSA from other neurodegenerative diseases, such as spinocerebellum, difficult. Close follow up is recommended.
ER  -