TY  - BOOK
AU  - Nagano, Heliza Marie S., MD.
TI  - A Documented case of fulminant type 1 diabetes mellitus in Filipino male / 
AV  - MED 2020 0009 
PY  - 2020///
CY  - Fairview, Quezon City
PB  - Department of Internal Medicine, FEU-NRMF
KW  - fulminant type 1 diabetes
KW  - diabetic ketoacidosis
KW  - type 1 diabetes
KW  - C-peptide
KW  - anti-GAD
KW  - glycosylated hemoglobin
N1  - Includes bibliographical references; RESDM
N2  - Abstract:  Genetic susceptibility and environmental factors contribute a major role in Diabetes Mellitus. In type 1 diabetes melllitus, there are two subcategories which is immune mediated (1A) and idiopathic (1B), which is regarded as fulminant type. If not recognized and treated early, the prognosis of this type has increased mortality within 24 hours because of the rapid and complete destruction of the pancreatic beta cell. The established diagnostic criteria includes ketoacidosis, elevated plasma glucose ≥288mg/dl with hemoglobin A1c <8.5% at onset, negative autoantibodies and low C-peptide levels.  This paper aims to discuss its unique features in a 30 year old Filipino male who is non-diabetic presented with one day history of abdominal pain and vomiting with no other associated signs and symptoms, apparently with abrupt signs of gyperglycemiaand onset of ketoacidosis. On work up, showed hyperglycemia with above normal glycosylated hemoglobin, elevated pancreatic enzymes, decreased C-peptide levels, negative islet related autoimmune antibodies (anti GAD, anti-insulin) and on ultrasound revealed fatty liver and prominent sized pancreas. Hence, fulminant type 1 diabetes mellitus was considered.
ER  -