TY - BOOK AU - Abesamis, Robert Glen R., MD. AU - Cruz, Ivy Viola, MD. AU - Infante, Joan Marie M., MD. TI - When two becomes one : : a case report on single umbilical artery / AV - PATH 2020 0001 PY - 2020/// CY - Fairview, Quezon City PB - Department of Pathology, FEU-NRMF N1 - Includes appendices and bibliographical references; RESDPLD N2 - Abstract: Single umbilical Artery (SUA) is a common abnormality of the umbilical cord but is only present in about 1-5&of pregnancies. It is more common in twin pregnancies than singletons, and congenital malformations are some of the adverse outcomes of SUA. This case report aims to discuss a variant of SUA seen in a preterm neonate with multiple congenital anomalies (Pulmonary Hypoplasia, Renal Agenesis, Complete Left Lip and Palate, Rocker Bottom Feet). The SUA was initially diagnosed on Congenital Anomaly scan during the second trimester, along with the congenital anomalies mentioned. The neonate was delivered, however eventually succumbed. The placenta was submitted for histopathologic examination, and revealed a single umbilical artery with a discordant of hypoplastic secont artery. The hypoplastic variant is seen lass frequently than the two-vessel single umbilical artery, and its diagnosis is aided by ultrasonography in the antenatal period. Histologic examination of the number of vessels and the remnants of the muscular layer of the hypoplastic vessel confirms the diagnosis. ER -