TENder reaction : a case of an 11-year old adolescent with toxic epidermal necrolysis - a case report / Charito P. Delmendo. - Fairview, Quezon City: Department of Child Health, FEU-NRMF, 2020. - tables; (in folder) with CD (soft copy).

Includes appendices and bibliographical references.

Abstract: Toxic Epidermal Necrolysis (TEN) is a life-threatening, usually drug-induced, mucocutaneous disease, characterized by necrosis and epidermal detachment involving more than 30 percent of the total body surface area. It is potentially fatal, therefore, early recognition of the disease is paramount to a patient's survival. This is a case of an 11-year-old, female who presented with rashes for 2 days associated with intermittent fever who initially developed pruritic, maculopapular rashes on hands, feet, buttocks and inguinal area, with vesicular rashes in perioral area, which later on progressed to generalized erythematous to violaceous fluctuant bullae lesions. Varicella with secondary bacterial infection was considered due to the presence of maculo-vesiculopapular lesions on the hands, feet, buttocks and inguinal area. However, with further progression of rashes and formation of bullae in certain areas becoming generalized, a diagnosis of Steven Johnson Syndrome, the TEN eventually was made. In this case report, we discussed the history and clinical presentation of an 11-year-old female with TEN initially managed as a case of Varicella Infection. This case report aims to acquaint us with this condition as it may mimic other diseases and its immediate recognition is important because it carrier a greater risk and complications aside from the difference in management.

Research - Department of Child Health

CH 2020 0004