A Systematic review and meta-analysis on the long-term efficacy and safety of micro pulse diode laser transscleral cyclophotocoagulation in patients with glaucoma /
Rudolf Christian F. Palma; Julia Mercedes C. Villalva; Manolito R. Reyes.
- Fairview, Quezon City: Department of Ophthalmology, FEU-NRMF, 2021.
- 40 pages: illustrations, tables; (in folder) + with flash drive (soft copy).
Includes appendices
Abstract: This systematic review and meta-analysis aim to review available information that addresses the question regarding the long-term efficacy in intraocular pressure (IOP) control and reduction, and the complication rates of Micropulse Transscleral Cyclophotocoagulation in patients with glaucoma. CENTRAL, PubMed and Google Scholar were used as data sources. Studies that include glaucoma patients who underwent MP-TSCPC with one year or more post-operative follow-up with data on pre-and post-operative IOP and complications were considered. NHLBI Quality Assessment Tool was used for the included studies. The treatment effect measures were (1) weighted mean difference (WMD) for the IOP reduction and, (2) proportions for the complication rate. Outcome measures were reported with a 95% confidence interval (CI) and P < 0.05 was considered statistically significant. Analysis was performed using Microsoft Excel and Open Meta Analysis software. In this systematic review, thirteen studies were included in total. Ten were case series, two were observational cohorts, and one randomized controlled trial. Risk of bias studies showed low to moderate risk among the included studies. In random effects model the pooled weighted mean difference was -13.649 (95% CI: