TY - BOOK AU - Acedillo Leigh Ann R AU - Fermin, Miriam Louella D. TI - Neurosyphilis: a case report / : [author]: Acedillo Leigh Ann R., Fermin, Miriam Louella D. AV - OPH 2024 0001 PY - 2024/// CY - Fairview, Quezon City PB - Department of Ophtalmology, FEU-NRMF N1 - Includes bibliographical references; RESDOP N2 - ABSTRACT: Based on the 2020 data of the World Health Organization, seven million people worldwide were estimated to be infected with syphilis, predominantly on male having sex with male (MSM). Syphilis can invade the different organs which may include the central nervous system and the optic nerve. Diagnosing neurosyphilis requires a high index of suspicion since it may be a presenting feature of a systemic disease. This paper aims to present a case of a 37-year-old male with a clinical diagnosis of neurosyphilis. A37-year-old male who presented with optic neuritis secondary to neurosyphilis. The patient initially consulted a private ophthalmologist where he was diagnosed with optic neuritis of the right, prescribed with Methylprednisolone tablet and referred to a neuro-ophthalmologist and infectious disease specialist at our institution. Disc photo and fluorescein angiography on initial consult on the right eye revealed a hyperemic edematous disc and a delay in arm-to-retina transit time. Mid to late phase leakage was also noted on disc margins. Neurosyphilis is an emerging disease of concern. Syphilis is a progressive disease. Thus, early diagnosis is of importance so that appropriate management may be initiated ER -