TY  - BOOK
AU  - Abad-Vencio, Melinda R., MD.
AU  - Custodio, Myla V., MD.
TI  - Determination of ionized calcium level in type 2 diabetes mellitus patients compared to nondiabetic subjects at FEU-NRMF Medical Center from January to June 2011 : : a prospective study 
AV  - MED 2011 0002 
PY  - 2011///
CY  - Fairview, Quezon City
PB  - Department of Internal Medicine, FEU-NRMF
N1  - RESDM
N2  - Abstract:  Calcium is essential for insulin-mediated intracellular processsess in insulin-responsive tissues such as skeletal muscle and adipose tissue.  A suboptimal calcium status has been associated with diabetes in observational studies, but evidence from trials is lacking 99% of calcium is the bone as hydroxyapatite.  The remaining 1% is found mainly in plasma which exists in 3 major forms: approximately 50% is in the free or ionized form, which is the physiologically important fraction, 40% is bound to albumin, and the remaining 10% is in soluble complexes with anions such as bicarbonate, phosphate, and lactate.  This study aims to determineif there is correlation between low ionized calcium and type 2 diabetes mellitus.  In this prospective, cross sectional study, 40 diabetic and 45 nondiabetic patients are included with their ionized calcium checked at feu - nrmf Clinical Laboratory.  Results of the study showed that there is lower ionized calcium in type 2 diabetes mellitus patients than nondiabetic patients  (p  value  0.66).  However, ionized calcium is significantly lower in insulin-treated diabetics compared to those on oral antidiabetics (1.09+ 0.06 vs. 1.22+ 0.04; p  value <0.0001).  It was seen that ionized calcium is also decreased in patients with hypertension (P 0.02)
ER  -