TY - BOOK AU - Serrano, Joan A., MD. TI - Severe pyridostigmine toxicity : : a case report / AV - CH 2010 0007 PY - 2010/// CY - Fairview, Quezon City PB - Department of Child Health, FEU-NRMF N1 - Includes appendices and bibliographical references; RESDCH N2 - Abstract: A 13 months old, female diagnosed with congenital myasthenia gravis at 9 months maintained on Pyridostigmine at 15 mg/paper tablet taken 5 times a day with sudden difficulty of breathing, drooling of saliva and seizure. Patient was admitted at the pediatric intensive care unit and inderwent atropinization. Pyridostigmine toxicity in myasthenia gravis is a rare condition since the drug is given to patients based on their signs and symptoms and computed according to their age and weight. Diagnosis can be made based on the presenting clinical signs and symptoms supported by an assay. However, in this case, pyridostigmine assay is available in our country thus, diagnostic dilemma sets in. Such incident warrants investigation and prompt intervention. At present, no standard mode of treatment was established to follow when such case is encountered ER -