TY  - BOOK
AU  - Delos Reyes, Jhoanna O.
AU  - Abueg, Aileen Rodora M.
AU  - Acosta, Eric Emil M.
AU  - Aldaba, Aldrin A.
AU  - Angeles, Rhea Maureen S.
AU  - Balagtas, Zarina R.
AU  - Bello, Ma. Rema C.
AU  - Bobis, James Dennis M.
AU  - Bolivar, Jerome
AU  - Buenavente, Noriel L.
AU  - Catapang, Jeanette A.
AU  - Cabisudo, Cherry Veil G.
AU  - Collao, Raymond Felix M.
AU  - Comia, Jaybemi
AU  - Cortez, Cherry Y.
AU  - Dofiles, Marigil J.
AU  - Evangelista, Allan A.
AU  - Evangelista, Arnaldo L.
AU  - Evangelista, Maryliza P.
AU  - Fernando, Flordeliza S.A.
AU  - Gardiner, Irene L.
AU  - Hu, Tzy-Guei
TI  - A Comparative study on the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of isoniazid (INH) by international, multinational, and local drug companies
AV  - M CFM ND 0002 
CY  - Fairview, Quezon City
PB  - Department of Community and Family Medicine, FEU-NRMF.
N1  - Includes appendices and bibliographical references; THDCFM
N2  - Abstract:  The Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of Isoniazid manufactured by different Drug Companies were determined and investigated Six INH tablets were randomly chosen from the 4 selected Drug companies and were subjected to anti-microbial effectiveness testing in vitro using Broth Dilution Method. Results were analyzed using ANOVA and their cost-effectiveness were ascertained by comparing their unit price in relation to their bacteriostatic and bactericidal activity. It was found out that there was a significant difference in the antimicrobial effectiveness of the INH tablets from the selected Drug Companies. It was apparent that INH from Drug Company A, a multi-national drug companyy, exhibited the lowest concentration to inhibit tubercle bacilli growth as well as the lowest concentration to effectiively kill the tubercle colonies in the subcultures from non-turbid tubes. These INH tablets cost much more compared to the locally produced Isoniazid. However, the fact that its anti-microbial effectiveness is superior in comparison to the other INH tablets from the other Drug Companies it can be implied that it has the greatest advantage
ER  -