A COMPARATIVE STUDY ON THE EFFECTS OF HONEY AND SILVER SULFADIAZINE ON WOUND SIZE REDUCTION OF BURN-INDUCED SKIN OF CAVIA PORCELLUS
- QUEZON CITY FEU-NRMF 2004
- 9 PAGES
ABSTRACT: An experimental study design was utilized the effects of honey and silver sulfadiazine in reducing the size of the burn induced wounds in guinea pigs (Cavia porcelus). Three burns were induced on the right flanks and legs of eighteen subjects. Treatments of silver sulfadiazine and honey were topically applied on two of the wounds, while no treatment was given to one of the wounds (control). Treatments were applied night for seven days. The diameters of the wounds on the 1st and 7th day were obtained and were subjected to ANOVA and paired t-tests. ANOVA showed a significant reduction of the wound size on the treated wounds of all the subjects(f= 3.038; critical value= 2.80). Paired t-test showed that the most significant reduction of wound size were those wounds being the wounds treated with silver sulfadiazine (t= 5.928), followed by honey (t= 5.244) then the control (t- 4.115). The critical value for the paired t-test was 1.753. These results do accept the H hypothesis that honey in treatment for reduction of burn size is significant. The H hypothesis was also accepted since the t-values obtained from silver sulfadiazine and honey were statistically close.