000			01931nam a22002537a 4500
999			_c10070 _d10070
003			CH20160003
005			20240720152920.0
008			170804b xxu||||| |||| 00| 0 eng d
040			_cFEU-NRMF MEDICAL LIBRARY
041			_aEnglish
050			_aCH20160003
100			_a Reandelar, Hannah M., MD. _eauthor
245			_a"Epstein barr virus-associated hemophagocytic lymphohistiocytosis" / _cHannah M. Reandelar.
260			_aFairview, Quezon City _bDepartment of Child Health, FEU-NRMF, _c2016
300			_c(in folder)
336			_atext _2rdacontent
337			_aunmediated _2rdamedia
338			_avolume _2rdacarrier
504			_aIncludes bibliographical references.
520			_aABSTRACT: Hemophagocytic Lymphohistiocytosis (HLH) is the aggressive proliferation of activated macrophages and histiocytes, which phagocytose RBCs, WBCs, and platelets leading to the clinical symptoms. Incidence is reported to be 1.2 cases per million persons per year. However, unpublished observations estimate that the figures have slightly increased over time because of improved detection. This is a case of 5-year old female who presented with intermittent fever for one and a half month, who was initially treated as dengue hemorrhagic fever. However, due to the persistence of fever and concomitant pancytopenia, other differential diagnoses such as Leukemia, and Systematic Lupus Erythematosus were considered. On her second month of illness, she was finally diagnosed with HLH secondary to Epstein Barr virus infection. In the sad turn of events, the patient succumbed to the complications of HLH. This report, therefore, aims to discuss the clinical presentation and diagnosis of HLH, and why it should be considered as an important diagnosis consideration in patients who present prolonged fever. Treatment and prognosis will also be discussed.
521			_aRESDCH
887			_2RC-RC-0004-16
942			_2lcc _cRE