000			02865nam a22002537a 4500
999			_c10208 _d10208
003			MED20160009
005			20240720152930.0
008			171012b xxu||||| |||| 00| 0 eng d
040			_cFEU-NRMF MEDICAL LIBRARY
041			_aENGLISH
050			_aMED20160009
100			_aMorales, Marian M., MD. _eauthor
245			_aA Comparative study of the effectiveness of sodium picosulfate and lactulose as cleaning agents in bowel preparation for colonoscopy / _cMarian M. Morales and Roy Caballero.
260			_aFairview, Quezon City _bDepartment of Medicine, FEU-NRMF, _c2016
300			_a15 pages: _biilustrations, photos (some colored); _c(in folder)
336			_2text _ardacontent
337			_2unmediated _ardamedia
338			_2volume _ardacarrier
504			_aIncludes bibliographical references.
520			_aABSTRACT: Colonoscopy is one of the procedures used as a means of visualization of the lower gastrointestinal tract and is indicated in many GI diseases and often used as screening tool for colon cancer. The ideal preparation for colonoscopy should reliably empty the colon of all fecal material in a rapid fashion with no gross or histologic alteration of the colonic mucosa. The preparation should be safe, convenient, tolerable, and inexpensive. This study aims to compare the effectiveness of Sodium Picosulfate and Lactulose among patients as cleansing agents for bowel preparation prior to colonoscopy. This is a retrospective cohort study involving patients who underwent colonoscopy procedure. Chart review of patients was done including the bowel preparation used, timing of colonoscopy, co-morbidities, and indication for colonoscopy. The outcome is the effectiveness of the bowel preparation used was evaluated using a 5 point validated scale with good interobserver reliability (Aronchick scale). Results showed that side effects such as headache was higher among those with lactulose (3.3% VS 0%, P=0.024 while vomiting was higher in Pico group (9.2% vs 3.9%, p=0.064 yet the difference was not significant. Moreover, using the Aronchick scale, the difference of ratings in both groups in the different scale levels were not statistically significant wherein both had higher ratings in scale 2 (39.5% vs 44.1%, p=0.416) followed by scale 1 (32.2% vs 30.9%, p=0.805). In conclusion, there is no significant difference in using Lactulose and Sodium Picosulfate as bowel preparation for colonoscopy based on the Aronchick scale. Moreover, the timing of colonoscopy in patients with Lactulose and Sodium Picosulfate were not statistically associated with their effectiveness based on Aronchick scale assessment. There was also no significant deference between the two preparation in terms of side effects, namely nausea, vomiting and headache.
521			_aRESDM
700			_aDr. Roy Caballero _eadviser
942			_2lcc _cRE