000 02459nam a22003497a 4500
999 _c10290
_d10290
001 OB 2017 0004
003 PILC
005 20240720152936.0
008 171027b xxu||||| |||| 00| 0 eng d
040 _beng
_cFEU-NRMF MEDICAL LIBRARY
_erda
041 _aenglish
050 _aOB 2017 0004
245 _aA Wound that failed to heal :
_bhigh grade ovarian serous carcinoma associated with chronic schistosomiasis /
_cShiara Marriz T. Marquez.
260 _aFairview, Quezon City:
_bDepartment of Obstetrics and Gynecology, FEU-NRMF,
_c2017.
300 _bphotos;
_c(in folder) +
_ewith flash drive (soft copy).
336 _2rdacontent
_atext
337 _2rdamedia
_aunmediated
338 _2rdacarrier
_avolume
504 _aIncludes appendices and bibliographical references.
520 _aAbstract: Schistosomiasis has been established as a causative factor in urinary bladder cancer. Several literatures have also mentioned its association with liver, colorectal and cervical cancer. However, its role in ovarian malignancy has not been described. With the premise that long-standing inflammation secondary to chronic infection or irritation predisposes to cancer by allowing an environment that fosters genomic lesions and tumor initiation, we are left with an open question: Does chronic infection with schistosomiasis also predispose to ovarian cancer? In this paper, we present a case of a 54-year-old diagnosed with high grade serous carcinoma of the ovary and fallopian tube with a history of chronic infection with Schistosomiasis.My objective is to establish the association of chronic infection with Schistosomiasis and high grade serous carcinoma of the ovary. Chronic infection with Schistosomiasis might be a potential cause of ovarian carcinoma by promoting general inflammation and subsequently affecting key cellular processes.In this case, the infection caused neoplastic lesions in the right fallopian tube with subsequent seeding of malignant cells to the right ovary, indirectly causing the high grade serous ovarian carcinoma of the patient.
521 _aRESDOG
650 _aovarian carcinoma
650 _aovarian malignancy
650 _aserous carcinoma
650 _aschistosomiasis
650 _aschistosoma
650 _achronic inflammation
650 _aectopic schistosomiasis
650 _atubal intraepithelial carcinoma
700 _aMarquez, Shiara Marriz T., MD.
_eauthor
942 _2lcc
_cRU