000			01578nam a22001937a 4500
999			_c10297 _d10297
003			PILC
005			20240720152936.0
008			171027b xxu||||| |||| 00| 0 eng d
040			_cFEU-NRMF MEDICAL LIBRARY
041			_aENGLISH
050			_aRESRAD20170002
100			_aCastillo, Aileen K., M.D.
245			_aA Case Report on Multiple System Atrophy : The Hot Cross Bun Sign
260			_aQUEZON CITY _bFEU-NRMF _c2017
300			_aNO PAGE NO.
520			_aABSTRACT: Multiple System Atrophy (MSA) is a rare sporadic progressive neurologic disorder affecting the striatonigral, olivopontocerebellum and central autonomic degeneration with 0.6 new MSA cases arising per 100,000 persons per year; a prevalence of 4-5 cases per 100,000 persons. Although diagnosed clinically, current researches have played a role in the diagnosis of the aforementioned syndrome, documenting the presence of the hot cross bun sign in T2 weighted MR imaging. F.G. is a 48 year old male parking attendant presented with an insidious onset of gradual progressive staggering broad based gait, intention tremors, and slowness of activities for a year. It was associated with postural dizziness and increased frequency of urination. T2 weighted imaging demonstrated the hot cross bun sign and atrophy of the brainstem, cerebellum and/or middle cerebellar peduncle.Early clinical course and infratentorial atrophy makes differentiating MSA from other neurodegenerative diseases, such as spinocerebellum, difficult. Close follow up is recommended.
521			_aresearch
942			_2lcc _cRE