000			02651nam a22002417a 4500
999			_c10992 _d10992
003			OB20180002
005			20240720153041.0
008			180907b xxu||||| |||| 00| 0 eng d
040			_cFEU-NRMF MEDICAL LIBRARY
041			_aEnglish
050			_aOB20180002
100			_aDe Guzman, Marie Rheapaz, MD _eauthor
245			_aThe Malignant transformation of a dermoid cyst : _ba case report / _cMarie Rheapaz De Guzman.
260			_aFairview, Quezon City _bDepartment of Obstetrics and Gynecology, FEU-NRMF, _c2018
300			_bpholots (colored); _c(in folder)
336			_2text _ardacontent
337			_2unmediated _ardamedia
338			_2volume _ardacarrier
504			_aIncludes appendices and bibliographical references.
520			_aABSTRACT: The question weather patients with squamous cell carcinoma in a mature cystic teratoma should undergo conservative surgery or postoperative adjuvant treatment remains unresolved. Ovarian cancer is the second most common malignancy of the lower part of the female genital tract, occurring less frequently than cancers of the endometrium but more frequently than cancers of the cervix. Germ cell tumors are the second most frequent type of ovarian neoplasm and account for approximately 10-20% of all ovarian tumors. The most frequent germ cell tumor is the Mature Cystic Teratoma (Dermoid Cyst); overall, only 2% to 3% of germ cell tumors are malignant, and more than 80% of malignant transformations are squamous cell carcinomas arising from the ectoderm; the rest are carcinoid tumors or adnocarcinomas. There are currently no reliable procedures for the early detection of ovarian cancer. Available potential screening techniques have included pelvic examination, ultrasound examination, serum CA-125 determination and other tumor makers and combined modality approaches. A mass in the adnexa may be symptomatic or discovered incidentally on pelvic examination or imaging. There is no established definite treatment protocol available due to lack of research on this rare case, thus frozen Section of the affected ovary is imperative in dermoid cysts to ensure that it is benign. In both Gynecologic and General Surgical practice, frozen sections are utilized mainly to aid in the differentiation of benign from malignant disease. Determining the type of tumor and extent of surgery is very important in Gynecologic Oncology. In this report, we present a rare case of a mature cystic teratoma which found to be malignant on frozen section with Intraoperative Stage I-A, and therefore managed by cytoreductive surgery followed by chemotherapy.
521			_aRESDOG
942			_2lcc _cRE