000			01702nam a22002417a 4500
999			_c10993 _d10993
003			MED20180005
005			20240720153041.0
008			180910b xxu||||| |||| 00| 0 eng d
040			_cFEU-NRMF MEDICAL LIBRARY
041			_aEnglish
050			_aMED20180005
100			_aDe Leon, Maria Frances Noreen C., MD. _eauthor
245			_aCatastrophic antiphospholipid antibody syndrome in a 36-year old female with systemic lupus erythematosus / _cMaria Frances Noreen C. De Leon.
260			_aFairview, Quezon City _bDepartment of Internal Medicine, FEU-NRMF, _c2018
300			_bphotos (black and white); _c(in folder)
336			_2text _ardacontent
337			_2unmediated _ardamedia
338			_2volume _ardacarrier
504			_aIncludes bibliographical references.
520			_aABSTRACT: Antiphospholipid syndrome (APS) is a multisystem autoimmune condition characterized by vascular thromboses and/or pregnancy loss associated with persistently positive antiphospholipid antibodies (aPL). Catastrophic APS (CAPS) is the most severe form of APS with multiple organ involvement developing over a short period of time, usually associated with microthromnosis. This is a case of a 36-year old female with history of 2 pregnancy losses, admitted due to right upper quadrant pain and subsequently developed multisytemic organ failure. Patient presented with cerebrovascular infract, pleural effusion, renal failure, heart failure, and psychosis with positive titers for lupus anticoagulant and ANA. Refractory to pulse therapy and anticoagulation, rituximab regimen was then initiated which showed significant improvement in patient's condition.
521			_aRESDM
942			_2lcc _cRE