000			01679nam a22002417a 4500
999			_c10994 _d10994
003			OB20180003
005			20240720153042.0
008			180910b xxu||||| |||| 00| 0 eng d
040			_cFEU-NRMF MEDICAL LIBRARY
041			_aEnglish
050			_aOB20180003
100			_aDiño, Erness Mae T., MD. _eauthor
245			_aSwyer syndrome : _ba gonadal switch / _cErness Mae T. Diño.
260			_aFairview, Quezon City _bDepartment of Obstetrics and Gynecology, FEU-NRMF, _c2018
300			_billustrations (black and white), photos (colored); _c(in folder)
336			_2text _ardacontent
337			_2unmediated _ardamedia
338			_2volume _ardacarrier
504			_aIncludes appendices and bibliographical references.
520			_aABSTRACT: 46 XY complete gonadal dysgenesis of Swyer Syndrome is a rare type of Disorder of Sex Development (DSD). This is a case of 32-year old, nulligravid, who has primary amenorrhea, with normal internal and external female genitalia, but has underdeveloped secondary sexual characteristics. Biochemically, a hypergonadotropic hypogonadism state is depicted by the elevated luteinizing hormone (LH) at 33.53 mIU/ml and low serum estradiol level at <5.00 pg/ml. A 46 XY karyotype through chromosomal analysis established its diagnosis. ultrasound revealed small uterus with small bilateral ovaries. The patient had withdraw bleeding after 5 months of estrogen therapy, which was then shifted to combined oral contraceptive pills that led to development of the breast and regular menstruation. Bilateral gonadectomy was subsequently done due to the increased risk of gonadal malignant.
521			_aRESDOG
942			_2lcc _cRE