000			03167nam a22002417a 4500
999			_c11044 _d11044
003			MED20180009
005			20240720153046.0
008			180925b xxu||||| |||| 00| 0 eng d
040			_cFEU-NRMF MEDICAL LIBRARY
041			_aEnglish
050			_aMED20180009
100			_aPagdagdagan, Lydeleth B., MD. _eauthor
245			_aA Case of a 48 year old female who presented with acute aortic occlusion in the setting of takayasu arteritis / _cLydeleth B. Pagdagdagan.
260			_aFairview, Quezon City _bDepartment of Medicine, FEU-NRMF, _c2018
300			_billustrations and photos (black and white); _c(in folder)
336			_2text _ardacontent
337			_2unmediated _ardamedia
338			_2volume _ardacarrier
504			_aIncludes bibliographical references.
520			_aABSTRACT: Takayasu arteritis is a rare, chronic large vessel vasculitis of known etiology which predominantly effects women younger than 40 years of age. Symptoms are highly variable based on the location and extent of the stenosis, arterial occlusion, aneurysm, and thrombosis. In patient with Takayasu's arteritis, platelet and coagulation activities are significantly increased, leading to hypercoagulable state and thrombus formation.. It causes extend narrowing of the aorta with symptoms of acute inflammation, aortic coarctation affecting the cardiovascular system. It is therefore considered to be important to perform aggressive immunosuppressive therapy and early revascularization to prevent symptoms and signs related to vascular stenosis and/ occlusion. Takayasu can be life-threatening by an occlusion of the ascending aorta and it's major branches, without any coronary arteries involvement. Acute Aortic Occlusion is rare, emergent vascular event which can arise secondary to the intimal fibrosis, thrombosis and calcifications of Takayasu Arteritis. Apart from constitutional complaints, nearly all patients with TA sooner or later present with symptoms and signs related to vascular stenosis and/or occlusion. They include hypertension with blood pressure differences in the extremities, pulse deficits, bruit, and upper and/or lower extremity claudications. Diagnosis is based on clinical presentation, relevant laboratory work-up, and imaging findings of wall thickening and stenosis of medium and large vessels. Management includes glucocorticoid therapy, frequently paired with adjunctive immunosuppressants, and sometimes surgical intervention in severe cases. Here, we present a unique case of Takayasu arteritis presenting with right upper extremity swelling, with severe narrowing of the brachiocephalic branch and left subclavian artery, near complete occlusion of the left common carotid artery, calcified proximal portions of the aortic arch branches and extensive calcification causing near complete narrowing seen from descending thoracic aortic down to the proximal abdominal aorta (before take off of celiac trunk. Based on our literature review, our article presents a very rare presentation of Acute aortic occlusion secondary from extensive aortic calcifications in Takayasu Arteritis patient .
521			_aRESDM
942			_2lcc _cRE