000			03004nam a22003737a 4500
999			_c11056 _d11056
003			PILC
005			20240720153047.0
008			181004b xxu||||| |||| 00| 0 eng d
040			_cFEU-NRMF MEDICAL LIBRARY
050			_aMT 2018 0002
100			_aMark Ryan V. Domingo _eadviser
111			_eRico 2018
245			_aAnti-Quorum Sensing Activity Capsicum Annuum (Family Solanaceae) Ethanolic Extract Against Serratia Marcescens / _cJohn Adriel Basco ; John Raphael Gollayan ; Christian Mher Dulce ; Ysabella De Jesus ; Frances Jimenez ; Mervin Franco ; Esperidion Immanuel Ibarra ; Shekinah Erin Mendoza ; Kristine Jamie Razon ; Angelika Victoria and Freddie Villajuan Jr.
260			_aFairview, Quezon City _bSchool of Medical Technology, FEU-NRMF, _c2018
300			_a39 pages: _billustrations, tables, photos; _c28 cm.
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
504			_aIncludes appendices and bibliographical references.
520			_aAbstract: Antibiotics are used as a treatment for diseases caused by medically important bacteria. However, multiple-drug resistant strains have emerged because of the use and misuse of these antibiotics. Most infectious diseases are caused by bacteria through several mechanisms, one of which is by the production of virulence factors. Some virulence factors of disease causing bacteria are associated with bacterial quorum sensing such as biofilm formation, release of toxic chemicals, enzymes, and others that contribute to bacterial pathogenicity. Inhibition of this mechanism, also known as quorum quenching, may cause attenuation of the production of these bacterial virulence factors. This study focuses primarily on exploring a natural quorum sensing inhibition activity of the crude extract of yellow bell pepper (Capsicum annuum)against the biofilm formation and other quorum sensing associated virulence factors of Serratia marcescens. the extract was tested against Serratia marcescens then determined if it had inhibited this organism's quorum sensing activity. This was then assessed by performing colorimetric method which identified if the plant extract affected biofilm formation, prodigiosin production, and motility-virulence factors of Serratia marcescens that are linked to quorum sensing. Crude Ethanolic extract of Yellow Bell pepper was concluded to have Antimotility as well as Anti-prodigiosin property in certain quantities.
521			_aTHMT
700			_aBasco, John Adriel _eauthor
700			_aGollayan, John Raphael _eauthor
700			_aDulce, Christian Mher _eauthor
700			_aDe Jesus, Ysabella _eauthor
700			_aJimenez, Frances _eauthor
700			_aFranco, Mervin _eauthor
700			_aIbarra, Esperidion Immanuel _eauthor
700			_aMendoza, Shekinah Erin _eauthor
700			_aRazon, Kristine Jamie _eauthor
700			_aVictoria, Angelika _eauthor
700			_aVillajuan, Freddie Jr. _eauthor
942			_2lcc _cTH