000 | 04484cam a22004337i 4500 | ||
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_c11790 _d11790 |
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001 | 19042212 | ||
003 | PILC | ||
005 | 20240831135357.0 | ||
008 | 160404s2016 enka b 000 0 eng d | ||
010 | _a 2016937843 | ||
020 | _a9780128030721 | ||
020 | _a0128030720 | ||
035 | _a(OCoLC)ocn938383554 | ||
040 |
_aYDXCP _beng _cFEU-NRMF MEDICAL LIBRARY _erda _dBTCTA _dBDX _dCDX _dOCLCO _dOCLCF _dOCLCQ _dSHH _dDRB _dDLC |
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042 | _alccopycat | ||
050 | 0 | 0 | _aRA 1231.M52 .Aa77 2016 |
082 | 0 | 4 |
_a615.9/253 _223 |
100 | 1 |
_aAaseth, Jan, _eauthor |
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245 | 1 | 0 |
_aChelation therapy in the treatment of metal intoxication / _cJan Aaseth, Guido Criponi, Ole Andersen. |
260 |
_aLondon, UK ; _aSan Diego, CA, USA : _bAcademic Press is an imprint of Elsevier, _c2016. |
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300 |
_axvi, 371 pages : _billustrations ; _c24 cm. |
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336 |
_atext _btxt _2rdacontent |
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337 |
_aunmediated _bc _2rdamedia |
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338 |
_avolume _bcr _2rdacarrier |
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504 | _aIncludes bibliographical references and index. | ||
505 | 0 | _aCover; Title Page; Copyright Page; Contents; Contributors; Preface; List of Abbreviations; Chapter 1 -- General Chemistry of Metal Toxicity and Basis for Metal Complexation; 1.1 -- General chemistry of metals; 1.2 -- Essential and nonessential elements; 1.3 -- Effects of toxic exposure of an essential or nonessential metal; 1.3.1 -- Basic Concepts in Chemical Toxicity Testing; 1.3.2 -- Exposure Patterns and Mechanisms of Metal Toxicity; 1.3.3 -- Gastrointestinal Effects of Metal Exposure; 1.3.4 -- Respiratory Effects of Metal Exposure; 1.3.5 -- Hepatic and Renal Effects. | |
505 | 8 | _a1.3.6 -- Effects on the Nervous System1.3.7 -- Hematological Effects; 1.3.8 -- Cardiovascular Effects; 1.3.9 -- Metal Allergies; 1.3.10 -- Carcinogenic Effects; 1.4 -- Basis for metal complex formation with endogenous and exogenous ligands; 1.5 -- Endogenous complexing and detoxification compounds; 1.5.1 -- Albumin; 1.5.2 -- Transferrin and Ferritin; 1.5.3 -- Glutathione; 1.5.4 -- Metallothionein; 1.5.5 -- Selenoproteins; 1.6 -- Conclusions; References; Chapter 2 -- Chelating Agents as Therapeutic Compounds-Basic Principles; 2.1 -- Chemical and biological principles for in vivo chelation; 2.1.1 -- Stability. | |
505 | 8 | _a2.1.2 -- Selectivity2.1.3 -- Kinetic Aspects of Chelation; 2.1.4 -- Absorption and Bioavailability of Chelating Agents; 2.2 -- Chelating agents: chemistry, kinetics, and toxicology; 2.2.1 -- BAL, DMPS, DMSA; 2.2.2 -- D-penicillamine; 2.2.3 -- Triethylenetetramine; 2.2.4 -- Deferoxamine, Deferiprone, and Deferasirox; 2.2.5 -- EDTA and DTPA; 2.2.6 -- Prussian Blue; References; Chapter 3 -- Diagnosis and Evaluation of Metal Poisonings and Chelation Therapy; 3.1 -- Introduction; 3.2 -- History of symptoms and exposure; 3.3 -- Clinical findings; 3.4 -- Genetic disorders with systemic metal accumulation. | |
505 | 8 | _a3.5 -- Toxicological analyses3.6 -- Biochemical measurements; 3.7 -- Physiological, radiological, and ultrasonographic investigations; References; Chapter 4 -- Chelation Treatment During Acute and Chronic Metal Overexposures-Experimental and Clinical Studies; 4.1 -- Introduction; 4.2 -- Aluminum; 4.2.1 -- Selected Representative Animal Studies; 4.2.2 -- Selected Representative Clinical Studies; 4.2.3 -- Conclusions; 4.3 -- Antimony; 4.3.1 -- Animal Experiments; 4.3.2 -- Clinical Cases; 4.3.3 -- Conclusion; 4.4 -- Arsenic; 4.4.1 -- Selected Animal Experiments; 4.4.2 -- Clinical Studies. | |
505 | 8 | _a4.4.3 -- Discussion and Conclusion4.5 -- Beryllium; 4.5.1 -- Experimental Chelation Studies; 4.5.2 -- Clinical Experience; 4.5.3 -- Conclusion; 4.6 -- Bismuth; 4.6.1 -- Animal Chelation Studies; 4.6.2 -- Clinical Chelation Studies; 4.6.3 -- Conclusion; 4.7 -- Cadmium; 4.7.1 -- Animal Chelation Experiments; 4.7.2 -- Clinical Chelation Studies; 4.7.3 -- Conclusion; 4.8 -- Chromium; 4.8.1 -- Animal Experimental Studies; 4.8.2 -- Clinical Cases; 4.8.3 -- Conclusion; 4.9 -- Cobalt; 4.9.1 -- Chelation, Animal Experiments; 4.9.2 -- Chelation, Clinical Studies; 4.9.3 -- Conclusion; 4.10 -- Copper. | |
505 | 8 | _a4.10.1 -- Animal Chelation Studies. | |
521 | _ailmu penyakit | ||
650 | 0 | _aChelation therapy. | |
650 | 7 |
_2Metals _xToxicology |
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700 | 1 | _aCriponi, Guido, | |
700 | 1 |
_aAndersen, Ole, _eauthor |
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856 |
_21 _yClick here to view TABLE OF CONTENTS and INDEX _uhttps://library.feu-nrmf.ph/cgi-bin/koha/opac-retrieve-file.pl?id=65e4b21a4b35a20c5fd36a4dec4580c6 |
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