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_d12014
001 OB 2020 0004
003 PILC
005 20240720153216.0
008 211027b xxu||||| |||| 00| 0 eng d
040 _beng
_cFEU-NRMF MEDICAL LIBRARY
_erda
041 _aenglish
050 _aOB 2020 0004
245 _aSynchronous endometrioid endometrial and serous ovarian carcinoma :
_ba gynecologic double jeopardy /
_cAna Victoria C. Crimen.
260 _aFairview, Quezon City:
_bDepartment of Obstetrics and Gynecology, FEU-NRMF,
_c2020.
300 _a34 pages:
_bphotos;
_c(in folder)
_ewith flash drive (soft copy).
336 _2rdacontent
_atext
337 _2rdamedia
_aunmediated
338 _2rdacarrier
_avolume
504 _aIncludes appendices and bibliographical references.
520 _aAbstract: Synchronous malignant tumors are two primary tumors diagnosed at the same time during surgery. A post-menopausal, nulligravid, presented with vaginal bleeding. Ultrasound revealed an endometrial and right ovarian mass, both with non-benign features. Cancer Antigen 125 and Human Epidydimis Protein 4 were elevated. She underwent Extrafascial Hysterectomy with Bilateral Salpingo-Oophorectomy with frozen section of Endometrium and Right Ovary, Bilateral Lymph Node Dissection. Histopathology report was Endometrioid Endometrial Carcinoma and High-Grade Serous Ovarian Carcinoma. The endometrial, ovarian, pelvic lymph nodes and the recto-sigmoid mass tissues positive for tumor cells were subjected to immunohistochemistry staining with Vimentin and Wilm's Tumor 1 (WT1), to establish which is the primary tumor and which tumor metastasized. The endometrial and ovarian tissues tested positive for Vimentin and WT1, respectively, suggesting both are primary independent tumors. The pelvic lymph nodes and recto-sigmoid lymph nodes tested positive for Vimentin and negative for WT1, suggesting endometrial tumor metastasis. The final diagnosis is Synchronous Endometrioid Endometrial Carcinoma Stage IIIC1 and High-Grade Serous Ovarian Carcinoma Stage IA, right ovary.
521 _aRESDOG
650 _aSerous Ovarian Carcinoma
650 _aEndometrioid Endometrial Carcinoma
650 _aNulligravid
650 _aWilm's Tumor 1
650 _aVimentin
650 _aSynchronous Malignant Tumors
700 _aCrimen Ana Victoria C., MD.
_eauthor
942 _2lcc
_cRU