000			02219nam a22003257a 4500
999			_c12038 _d12038
001			MED 2020 0009
003			PILC
005			20240720153218.0
008			211105b xxu||||| |||| 00| 0 eng d
040			_beng _cFEU-NRMF MEDICAL LIBRARY _erda
041			_aenglish
050			_aMED 2020 0009
245			_aA Documented case of fulminant type 1 diabetes mellitus in Filipino male / _cHeliza Marie S. Nagano.
260			_aFairview, Quezon City: _bDepartment of Internal Medicine, FEU-NRMF, _c2020.
300			_c(in folder).
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
504			_aIncludes bibliographical references.
520			_aAbstract: Genetic susceptibility and environmental factors contribute a major role in Diabetes Mellitus. In type 1 diabetes melllitus, there are two subcategories which is immune mediated (1A) and idiopathic (1B), which is regarded as fulminant type. If not recognized and treated early, the prognosis of this type has increased mortality within 24 hours because of the rapid and complete destruction of the pancreatic beta cell. The established diagnostic criteria includes ketoacidosis, elevated plasma glucose ≥288mg/dl with hemoglobin A1c <8.5% at onset, negative autoantibodies and low C-peptide levels. This paper aims to discuss its unique features in a 30 year old Filipino male who is non-diabetic presented with one day history of abdominal pain and vomiting with no other associated signs and symptoms, apparently with abrupt signs of gyperglycemiaand onset of ketoacidosis. On work up, showed hyperglycemia with above normal glycosylated hemoglobin, elevated pancreatic enzymes, decreased C-peptide levels, negative islet related autoimmune antibodies (anti GAD, anti-insulin) and on ultrasound revealed fatty liver and prominent sized pancreas. Hence, fulminant type 1 diabetes mellitus was considered.
521			_aRESDM
650			_afulminant type 1 diabetes
650			_adiabetic ketoacidosis
650			_atype 1 diabetes
650			_aC-peptide
650			_aanti-GAD
650			_aglycosylated hemoglobin
700			_aNagano, Heliza Marie S., MD. _eauthor
942			_2lcc _cRU