000			02107nam a22002537a 4500
999			_c12042 _d12042
001			CH 2020 0007
003			PILC
005			20240720153218.0
008			211105b xxu||||| |||| 00| 0 eng d
040			_beng _cFEU-NRMF MEDICAL LIBRARY _erda
041			_aenglish
050			_aCH 2020 0007
245			_aBrain on fire : _bAnti-N-Methyl D-Aspartate (NMDA) receptor encephalitis in a child / _cKatrina D. Balangue.
260			_aFairview, Quezon City _bDepartment of Child Health, FEU-NRMF, _c2020.
300			_btables; _c(in folder).
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
504			_aIncludes appendices and bibliographical references.
520			_aAbstract: Autoimmunine encephalitis occurs as a more common cause of pediatric encephalopathy than previously imagined. This has been challenging to most physicians. Differential diagnoses include infectious and post-infectious processes, systematic inflammatory conditions such as systematic lupus erythematosus, and primary CNS vasculitis. Newly recognized anti-neuronal antibody-mediated inflammatorydisorders such as anti-N-methyl-D-aspartatereceptor (NMDA) receptor encephalitis have become an important diagnostic consideration in children presenting with severe newly acquired neuropsychiatric symptoms. Here, we present a male pediatric patient who initially manifested with seizures disorder. The seizure disorder was eventually accompanied with involuntary movements, described as chorea-like, associated with psychiatric symptoms. Anti-NMDA receptor encephalitis was entertained, and confirmed by presence of antibodies to the NMDA receptors in the CSF. Hence, he was started on methylprednisolone. His symptoms worsened and eventually he was transffered to the intensive care unit. Unfortunately, he expired due to unmanageable autonomic dysfunction. Critical care management of Anti-NMDA receptor encephalitis can be further investigated to help improve treatment strategies.
521			_aRESDCH
700			_aBalangue, Katrina D., MD. _eauthor
942			_2lcc _cRU