000			03068nam a22004217a 4500
999			_c12216 _d12216
001			MT 2022 0006
003			PILC
005			20240720153237.0
008			220309b xxu||||| |||| 00| 0 eng d
040			_beng _cFEU-NRMF MEDICAL LIBRARY _erda
041			_aenglish
050			_aMT 2022 0006
245			_aThe Use of plant-based alternative in vitro anticoagulant in diagnostic laboratory : _ba systematic review / _cAl Daniel S. Abagatnan, Samantha Nicole P. Allera, Joshua Christian L. Estanislao, Jelline Mae A. Estipular, Kim Princes R. San Diego, Gil Clinton S. Tesorero; Richard Rupert T. Vicencio.
260			_aFairview, Quezon City : _bSchool of Medical Technology, FEU-NRMF, _c2022.
300			_a70 pages: _billustrations, tables, photos; _c28 cm.
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
504			_aIncludes appendices and bibliographical references.
520			_aAbstract: A routine examinations to evaluate for abnormalities in health usually includes laboratory tests. Anticoagulants are commonly used to supress the coagulation process in vitro and in vivo. Furthermore, blood collection tibes used in clinical laboratories contain anticoagulants to preserve the blood samples intheir fluid state. Hence, this study aimed to determine the use of plant-based alternative in vitro anticoagulants in diagnostic laboratories. This study focused on the anticoagulant capability, chemical components of the plant-derived in vitro anticoagulants, and their effects on the blood cells. The researchers gathered data from different databases such as PubMed, Google Scholar, ResearchGate and EBSCohost. The most important criteria of the journal articles included must have PT and aPTT results. A total of 46 plants and 61 extracted major chemical constituents are involved in the study. The highest aPTT and PT results were found in Thymus atlanticus and Thymus zygis. It revealed that flavonoids are the most common chemical constituents in the study. Chemical constituents may or may not affect the blood cells. In the study, The researcher found out that the most common toxic effect of some chemical constituents is the alteration of blood cell count. The most anticoagulant activity was seen in Thymus atlanticus and Thymus zygis, thus, study concluded that to be the most efficient plant-based alternative in vitro anticoagulants.
521			_aTHMT
650			_aanticoagulants
650			_aanticoagulant activity
650			_aanticoagulant tubes
650			_aplant
650			_aalternative anticoagulant
650			_aplant-based anticoagulant
650			_aPT
650			_aaPTT
700			_aAbagatnan, Al Daniel S. _eauthor
700			_aAllera, Samantha Nicole P. _eauthor
700			_aEstanislao, Joshua Christian L. _eauthor
700			_aEstipular, Jelline Mae A. _eauthor
700			_aSan Diego, Kim Princes R. _eauthor
700			_aTesorero, Gil Clinton S. _eauthor
700			_aVicencio, Richard Rupert T., RMT _eadviser
942			_2lcc _cRU