000 02545nam a22003257a 4500
999 _c12283
_d12283
001 OB 2021 0001
003 PILC
005 20240720153244.0
008 220427b xxu||||| |||| 00| 0 eng d
040 _beng
_cFEU-NRMF MEDICAL LIBRARY
_erda
041 _aenglish
050 _aOB 2021 0001
245 _aComparison of the effect of miconazole and clotrimazole in the treatment of vulvovaginal candidiasis among women seen in a tertiary medical center from 2016 to 2020 /
_cShiara Marriz Marquez; Lylah Reyes.
260 _aFairview, Quezon City:
_bDepartment of Obstetrics and Gynecology, FEU-NRMF,
_c2021.
300 _a29 pages:
_btables;
_c(in folder) +
_ewith flash drive (soft copy).
336 _2rdacontent
_atext
337 _2rdamedia
_aunmediated
338 _2rdacarrier
_avolume
504 _aIncludes appendices and bibliographical references.
520 _aAbstract: Vulvovaginal candidiasis (VVC) is one of the frequent infections of the female genital tract and is the second most common cause of vaginal infections after bacterial vaginosis. According to the Center for Disease Control and Prevention (CDC), azoles are the first-line of treatment for VVC. Among the azoles available in the Philippines, only miconazole and clotrimazole are recommended for both pregnant and non-pregnant women. This study reviewed a total of 316 records of patients, regardless of pregnancy status who were given either single dose 1200 mg miconazole or a 6-day 100 mg clotrimazole vaginal suppository and treatment for vulvovaginal candidiasis. Upon follow-up, 11 out of 316 (3.46%) were still symptomatic which was noted in 2 (18.1%) from the miconazole group while 9 (81.8%) from the clotrimazole group. The difference for these outcome between the treatment groups is statistically significant. With regards to treatment failure rate, for miconazole it is 1.2% (2/161) while for clotrimazole, it is 5.8% (9/155). None of the charts of these women had recorded adverse reaction to the given treatment. In conclusion, the single-dose miconazole regimen has a significant higher clinical cure rate than the 6-day clotrimazole. It has the potential to improve patient compliance and improve treatment outcome at a lower cost.
521 _aRESDOG
650 _avulvovaginal candidiasis
650 _amiconazole
650 _aclotrimasole
650 _aazole antifungals
650 _avaginitis
700 _aMarquez, Shiara Marriz, MD.
_eprincipal investigator
700 _aReyes, Lylah, MD.
_eco-author
942 _2lcc
_cRU