000			02139nam a22003017a 4500
999			_c12288 _d12288
001			OB 2021 0006
003			PILC
005			20240720153244.0
008			220428b xxu||||| |||| 00| 0 eng d
040			_beng _cFEU-NRMF MEDICAL LIBRARY _erda
041			_aenglish
050			_aOB 2021 0006
245			_aLymphocyte immunotherapy in recurrent pregnancy loss : _ba case report / _cJoana Jo R. Ludovica.
260			_aFairview, Quezon City: _bDepartment of Obstetrics and Gynecology, FEU-NRMF, _c2021.
300			_a25 pages: _bphotos; _c(in folder) + _ewith flash drive (soft copy).
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
504			_aIncludes appendices and bibliographical references.
520			_aAbstract: Recurrent Pregnancy Loss (RPL) is a multifactorial condition defined as having two or more consecutive pregnancy losses. Investigation of the well-established causes is warranted to increase the chance of subsequent good pregnancy outcome. However, 50% of the RPL cases remains unexplained. Pregnancy involves shift in the immunologic response to initiate immune tolerance. Deviation from the normal immune tolerance response may lead to pregnancy failure and is the proposed mechanism of unexplained recurrent pregnancy loss. Lymphocyte immunotherapy, which involves transfusion of paternal leukocytes to the maternal peripheral blood to induce an immune response creating a conducive environment for pregnancy maintenance, is a proposed therapy for unexplained RPL. This is a case report of a 40 year old, Gravida 7 Para 1, with Recurrent Pregnancy Loss, with no known genetic, uterine, and coagulation anomalies who initially underwent assisted reproductive techniques with Intrauterine Insemination and eventually underwent 4 cycles of Lymphocyte Immunotheraphy, and was able to conceive and deliver at term.
521			_aRESDOG
650			_arecurrent pregnancy loss
650			_alymphocyte immunotherapy
650			_aimmune tolerance
650			_aalloimmune pregnancy
700			_aLudovica, Joana Jo R., MD. _eauthor
942			_2lcc _cRU