000			02030nam a22002537a 4500
001			R000769
003			PILC
005			20240720153335.0
008			240717b |||||||| |||| 00| 0 eng d
040			_beng _cFEU-NRMF MEDICAL LIBRARY _drda
041			_aeng
050			_aMED 2024 0002
245			_aA 26-year-old female with Wolfram-associated Syndrome: A case report / _b[author]: Sicat, Arline
260			_aFairview, Quezon City: _bDepartment of Internal Medicine, FEU-NRMF, _c2024
300			_c(in folder) _ewith flash drive (soft copy)
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
504			_aIncludes bibliographical references
520			_aABSTRACT: Wolfram syndrome is a very rare autosomal recessive disease characterized by constellation symptoms progressing from childhood to adulthood. These symptoms brought forth its other name DIDMOAD which comprises Diabetes insipidus, Diabetes mellitus, Optic Atrophy and Deafness. In this report, we describe a young woman diagnosed with Type 1 diabetes and optic atrophy who consulted due to severe headache, fever, urinary frequency and urgency. During the course of her admission, she had symptoms of persistent thirst, polyuria and nocturia. Further workup confirmed that she had urological abnormalities and Diabetes insipidus leading to a diagnosis of Wolfram-associated Syndrome. As healthcare providers, a high suspicion for Wolfram Syndrome should be a standard in patients who present with juvenile onset diabetes mellitus and optic atrophy which are the primary symptoms of Wolfram Syndrome. Early recognition and diagnosis will guide us to the proper management and help improve the patient and their family's quality of life. Objectives: 1. To present a case of a 26-year-old female who is a case of Wolfram associated Syndrome 2. To discuss the approach to diagnosis and management of patients with Wolfram Syndrome
521			_aRESDM
700			_aSicat, Arline _eauthor
942			_2lcc _cRU
999			_c12730 _d12730