000 02226nam a22002537a 4500
001 R000747
003 PILC
005 20240806140530.0
008 240806b |||||||| |||| 00| 0 eng d
040 _beng
_cFEU-NRMF MEDICAL LIBRARY
_drda
041 _aeng
245 _aCorneal endothelial cell density and morphology of FILIPINO patients in a tertiary level hospital /
_b[author]: Villalva, Julia Mercedes C., Galvante, Pia Regina E.
260 _aFairview, Quezon City:
_bDepartment of Ophtalmology, FEU-NRMF,
_c2023
300 _c(in folder)
_ewith flash drive (soft copy)
336 _2rdacontent
_atext
337 _2rdamedia
_aunmediated
338 _2rdacarrier
_avolume
504 _aIncludes bibliographical references.
520 _aABSTRACT: The effects of diabetes melitus and hypertension on the corneal endothelium are often underestimated. Several studies revealed contradicting results on whether there is a statistically significant correlation. This study identified the demographics and corneal endothelial cell density and morphology of diabetic and hypertensive patients 20-83 years old who underwent specular microscopy in one center from January 2021 to January 2023 and compared it with an age-matched control. There was no significant correlation between mean cell density, coefficient of variation and hexagonality in patients with either of the comorbidities and those without across all age groups. However, for patients 60 years old and above, endothelial cell count decreased by an average of 0.78% (18.8003 cells/mm2), and percent hexagonality decreased by an average of 28.2% (-13.31%) compared to age-matched control. The majority of the population with comorbidities was noted to belong to this age group. Therefore, it is highly recommended to include careful evaluation of the corneal endothelium as part of the diabetic and hypertensive patient’s eye screening, especially in pre-operative examination. Keywords: corneal endothelium, cell density, cell morphology, specular microscopy, Diabetes Meilitus, Hypertension
521 _aeynayim
_aRESDOP
700 _aVillalva, Julia Mercedes C.,
_eauthor
700 _aGalvante, Pia Regina E.
_eauthor
942 _2lcc
_cRU
999 _c12971
_d12971