000			01801nam a22002657a 4500
001			R000748
003			PILC
005			20240807093957.0
008			240807b |||||||| |||| 00| 0 eng d
040			_beng _cFEU-NRMF MEDICAL LIBRARY _drda
041			_aeng
050			_aMED 2023 0007
245			_aHypothermia as neuroprotectant during acute ischemic stroke: a meta-analysis / _b[principal investigator]: Roxas, Gina Marie M.
260			_aFairview, Quezon City: _bDepartment of Internal Medicine, FEU-NRMF, _c2023
300			_c( in folder ) _ewith flash drive (soft copy)
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
504			_aIncludes bibliographical references.
520			_aABSTRACT: Acute ischemic stroke is considered the leading cause of disability worldwide and the 3rd leading cause of death, its neurological outcome is secondary to vascular occlusions which leads to brain tissue ischemia. It is known that infarct progress in a circumferential fashion towards its maximum volume over 7 hours. This study aims to explain the effect of maintaining hypothermia during acute ischemic stroke. There is a noted decrease in the cerebral metabolic rate by 7-10%for every degree Celsius reduction in body temperature which explain the improvement of the NIHSS score among patient maintained with a core body temperature of 32-35 degrees as shown in the results with a p value of less than 0.05 compared to patient maintained on core body temperature. Improvement upon follow-up was seen by using MRS scoring, there is noted significant association between hypothermia and a lower level of MRS.
521			_arefooah _aRESDM
700			_aRoxas, Gina Marie M. _ePrincipal investigator
856			_21
942			_2lcc _cRE
999			_c12992 _d12992