000			01383nam a22002417a 4500
999			_c7888 _d7888
001			4880
003			PILC
005			20240720152603.0
008			160505b2009 xxu||||| |||| 00| 0 eng d
040			_cFEU-NRMF MEDICAL LIBRARY
041			_aEnglish
050			_aRES RAD 2009 0001
100			_aChan, Gerald S. , M.D.
245			_aA Rare Diffuse Large B-Cell Lymphoma of the Brain: A case Report
264		0	_c2009
336			_aText
337			_aUnmediated
338			_aVolume
502			_bMEDICINE _gResearch project
520			_aDiffuse large B-Cell lymphoma (DLBCL) is an aggressive and fast-growing lymphoma. It can arise outside of the lymphatic system like in the brain. The mechanism for the involvement of the brain by malignant B lymphocytes is still unknown. Gene expression studies and other molecular approaches provide useful information abut DLBCL for the management and treatment. Presented is a case of a 37 year old, male with slurring of speech and word finding difficulty. Neuroimaging studies like CT-scan, CE-MRI, DWMRI and MR spectroscopy are obtained that raise the suspicion of PCNSL. Brain biopsy sampling remains the gold standard for PCNSL diagnosis and requires hispathological and immunohistochemistry. Methothrexatebase regimens even without radiation prolong survival to over 5 years.
887			_aRES RC0015
942			_2lcc _cRE