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001 MED 2013 0008
003 PILC
005 20240720152609.0
008 160505b2013 xxu||||| |||| 00| 0 eng d
040 _beng
_cFEU-NRMF MEDICAL LIBRARY
_erda
041 _aenglish
050 _aMED 2013 0008
245 _aComparison of the predictive value of CHADS2 and CHA2DS2 VASc among Filipino patients with coronary artery disease without atrial fibrillation for ischemic stroke admitted at FEU-NRMF from 2009-2012
_ba case control study /
_cRamil Y. Macapagal, Greg V. Dayrit and Ramon Pineda.
260 _aFairview, Quezon City:
_bDepartment of Internal Medicine, FEU-NRMF,
_c2013.
300 _billustrations, tables;
_c(in folder)
336 _atext
_2rdacontent
337 _aunmediated
_2rdamedia
338 _avolume
_2rdacarrier
504 _aIncludes bibliographical references.
520 _aAbstract: The CHADS2 score and other similar risk stratification schemes have proven useful in populations with known Atrial Fibrillation, the vast majority (85%) of ischemic occur in individuals without known Atrial Fibrillation. Patients with coronary heart disease (CHD) are at increased risk for stroke, and each of the component comorbidities of the CHADS2 score has been independently associated with stroke in large cohorts of patients with Coronary Heart Disease. CHA2DS2-VASc a new scoring system for risk stratification among atrial fibrillation for ischemic stroke is the modification of CHADS2 score. The study evaluates the CHADS score and CHA2DS2-VASc score for prediction of ischemic stroke/TIA among Filipino patients with Coronary Heart Disease without Atrial Fibrillation at FEU-NRMF. This is a Case Control Study. All Filipino patients with Coronary Artery Disease without Atrial Fibrillation with Ischemic Stoke (Case) or without Ischemic stroke (Control) were studied. CHADS2 (congestive heart failure (CHF), Hypertension, ageā‰„ 75, diabetes (1 point each), and prior stoke or transient ischemic attack (TIA) (2 points) and the CHA2DS2-VASc (CHA2DS2-Vascular disease, Age 65-74 years, Sex category) (1 point each) score were calculated. A total of 752 subjects were studied, among them 188 subjects have ischemic stroke. In comparison of CHADS2 and CHAD2DS2-Vasc scoring between cases and controls, the results showed that there was a significant difference noted as proven by the p values 0.001 and 0.008 respectively. The CHAD2DS2-Vasc scoring of cases were significantly higher than controls. The CHADS2 risk score and the CHAD2DS2-Vasc risk score have a significant predictive value for Ischemic Stroke/TIA among patients with Coronary Artery Disease without Fibrillation. Also, CHAD2DS2-Vasc risk score comparing CHADS2 risk score due to its additional non-major stroke risk factors may be better in discriminating between patients at a low and high risk of stoke. The 2 scoring system may also have role in identification of high-risk individuals who may benefit from stroke prevention therapies or screening for silent atrial fibrillation.
521 _aRESDM
700 _aMacapagal, Ramil Y., MD.
_eprincipal investigator
700 _aDayrit, Greg V., MD.
_esupervising investigator
700 _aPineda, Ramon, MD.
_esupervising investigator
942 _2lcc
_cRU