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001 | MED 2011 0002 | ||
003 | PILC | ||
005 | 20240720152612.0 | ||
008 | 160505b2011 xxu||||| |||| 00| 0 eng d | ||
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_beng _cFEU-NRMF MEDICAL LIBRARY _erda |
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041 | _aenglish | ||
050 | _aMED 2011 0002 | ||
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_aDetermination of ionized calcium level in type 2 diabetes mellitus patients compared to nondiabetic subjects at FEU-NRMF Medical Center from January to June 2011 : _ba prospective study / _cMelinda R. Abad-Vencio and Myla V. Custodio. |
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_aFairview, Quezon City: _bDepartment of Internal Medicine, FEU-NRMF, _c2011. |
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_a19 pages: _billustrations; _c(in folder) |
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_atext _2rdacontent |
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_aunmediated _2rdamedia |
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_avolume _2rdacarrier |
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520 | _aAbstract: Calcium is essential for insulin-mediated intracellular processsess in insulin-responsive tissues such as skeletal muscle and adipose tissue. A suboptimal calcium status has been associated with diabetes in observational studies, but evidence from trials is lacking 99% of calcium is the bone as hydroxyapatite. The remaining 1% is found mainly in plasma which exists in 3 major forms: approximately 50% is in the free or ionized form, which is the physiologically important fraction, 40% is bound to albumin, and the remaining 10% is in soluble complexes with anions such as bicarbonate, phosphate, and lactate. This study aims to determineif there is correlation between low ionized calcium and type 2 diabetes mellitus. In this prospective, cross sectional study, 40 diabetic and 45 nondiabetic patients are included with their ionized calcium checked at feu - nrmf Clinical Laboratory. Results of the study showed that there is lower ionized calcium in type 2 diabetes mellitus patients than nondiabetic patients (p value 0.66). However, ionized calcium is significantly lower in insulin-treated diabetics compared to those on oral antidiabetics (1.09+ 0.06 vs. 1.22+ 0.04; p value <0.0001). It was seen that ionized calcium is also decreased in patients with hypertension (P 0.02). | ||
521 | _aRESDM | ||
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_aAbad-Vencio, Melinda R., MD. _eprincipal investigator |
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_aCustodio, Myla V., MD. _esupervising investigator |
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887 | _aND | ||
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_2lcc _cRU |