000			02553nam a22002537a 4500
999			_c8197 _d8197
003			MED20070003
005			20240720152619.0
008			160505b2007 xxu||||| |||| 00| 0 eng d
040			_cFEU-NRMF MEDICAL LIBRARY
041			_aEnglish
050			_aMED20070003
100			_aLucas, Paul C., MD. _eauthor
245			_aChronic anaerobic osteomyelitis of the foot / _cPaul C. Lucas.
260			_aFairview, Quezon City _bDepartment of Medicine, FEU-NRMF, _c2007
300			_a12 pages: _c(in folder)
336			_2text _ardacontent
337			_2unmediated _ardamedia
338			_2volume _ardacarrier
504			_aIncludes appendices and bibliographical references.
520			_aABSTRACT: Osteomyelitis is a difficult to treat infection, which can only occur after a very large inocula, trauma or the presence of foreign bodies, which require long term therapy. It is usually caused by Staphylococcus aureus, a gram positive cocci and caused by other organisms such as Actinomyces. We are presenting a 34 year old male, who initially presented with soft tissue mass at the right after a trauma, with no other signs and symptoms noted such as fever. Physical examination then was unremarkable. The patient underwent excision biopsy of the mass at the right foot and microsections of which showed fibrocollagenous and fibroadipose tissue with large, basophilic staining bacterial colonies surrounded by liquefaction necrosis, in which it has numerous inflammatory cells, comprised predominantly with neutrophils admixed with lymphocytes. The finding then was consistent with actinomycosis. The patient was initially given Prostaphlin 500 mg/cap, QID for 7 days as home medication. The patient was recurrently admitted due to non-healing lesion at the right foot where he was given repeatedly with parenteral and oral antibiotic therapy, which offered temporary resolution of the lesion. An x-ray of the right foot was done revealing osteomyelitis. Another biopsy of the affected area showed acute and chronic non-specific inflammation with abscess and osteomyelitis. Penicillin was continued and ESR monitoring was done. The patient then remain asymptomatic. There are reported cases of osteomyelitis caused by actinomycosis in different sites treated by long term antibiotics therapy. This case is a reportable case in the Philippines and long term antibiotic therapy together with patients awareness of the clinical outcome of the disease contribute to better prognosis.
521			_aRESDM
887			_aR00236
942			_2lcc _cRE