000 02224nam a22002537a 4500
999 _c8199
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003 MED20070001
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008 160505b2007 xxu||||| |||| 00| 0 eng d
040 _cFEU-NRMF MEDICAL LIBRARY
041 _aEnglish
050 _aMED20070001
100 _aMerin, Edelweise G., MD.
_eauthor
245 _aA Case of 45-year-old female with systemic lupus erthematosus presenting as central nervous system vasculitis /
_cEdelweise G. Merin.
260 _aFairview, Quezon City
_bDepartment of Medicine, FEU-NRMF,
_c2007
300 _bphotos;
_c(in folder)
336 _2text
_ardacontent
337 _2unmediated
_ardamedia
338 _2volume
_ardacarrier
504 _aIncludes appendices and bibliographical references.
520 _aABSTRACT: Vasculitis may involve the nervous system (CNS), including Bechey`s disease, polyarteritis nodosa, vasculitis associated with connective tissue disease such as lupus (systemic lupus erythematous; SLE), No other forms of vasculitis is as difficult to diagnose as CNS vasculitis. We are presenting a 45- year-old female who had headache, vomiting and sudden loss of consciousness. Pertinent physical examination revealed patchy blind spots in visual fields, Bipedal pitting edema and Raynaud`s phenomenon and arthritis were noted. Can read simple words but with difficulty in writing due to weakness. Diffusion weighted MRI (BRAIN) done revealed markedly FLAIR - hyperintense (subtley hyperitense of T2 - diffusion and T2W images) cortical lesions in occipital and right parietal lobes. EEG done showed slowing of electrical impulses on the bifrontal areas which tends to be more ectensive as compared to the MRI result. Initial CSF findings showed leukocytosis with predominance of segmenters, CSF IgG was elevated, ANA titer and CRP positive are all suggestive of vasculitic syndrome. Anti -ds DNA was positive which confirmed the diagnosis of SLE as the cause of the CNS vasculitis. The primary treatment to vasculitis is immunosuppressive therapy, patient was started with Methylprednisolone. Patient was followed up closely and gradually improved without neurologic dificits.
521 _aRESDM
887 _aR00240
942 _2lcc
_cRE