000 01829nam a22002537a 4500
999 _c8243
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003 MED20100001
005 20240720152621.0
008 160505b2010 xxu||||| |||| 00| 0 eng d
040 _cFEU-NRMF MEDICAL LIBRARY
041 _aEnglish
050 _aMED20100001
100 _aAcosta, Charmaine D., MD.
245 _aBenzene associated aplastic anemia presenting 10 years after exposure case report /
_cCharmaine D. Acosta.
260 _aFairview, Quezon City
_bDepartment of Medicine, FEU-NRMF,
_c2010
300 _c( in folder)
336 _atext
_2rdacontent
337 _aunmediated
_2rdamedia
338 _avolume
_2rdacarrier
504 _aIncludes appendices and bibliographical references.
520 _aABSTRACT: Aplastic anemia is a syndrome characterized by reticulocytopenia, neutropenia, monocytopenia, and thrombocytopenia and replacement of the marrow with fat and a near absence of hematopoietic precursor cells. Most cases occur without an evident precipitating cause and result from expression of autoreactive T lymphocytes that suppress or destroy primitive hematopoietic cells while some cases are due to toxic effect of chemicals or drugs. Here I present a case of aplastic anemia that occured initially a decade after inciting agent has been removed. The case is E.I., 54-year old, male, Filipino who presented with easy fatigability that started 3 months prior to admission. Complete blood count revealed anemia, thrombocytopenia, and leukopenia. Peripheral blood smear showed paucity of blood cells with the bone marrow aspirate revealing hypocellularity. Patient underrwent blood transfusion of seven units of packed red blood cells. He was then discharged with modest improvement in the patient`s complete blood count.
521 _aRESDM
887 _aRES RC 0002
942 _2lcc
_cRE