000			02355nam a22002657a 4500
999			_c8668 _d8668
001			M BIO 2013 0004
003			PILC
005			20240720152652.0
008			160505b2013 xxu||||| |||| 00| 0 eng d
040			_beng _cFEU-NRMF MEDICAL LIBRARY _erda
041			_aenglish
050			_aM BIO 2013 0004
245			_aFree radical scavenging activity of the methanolic crude leaf extracts of cananga odorata and jasminum sambac / _cSection 1-A2; Hena Alcantara.
260			_aFairview, Quezon City: _bDepartment of Biochemistry, FEU-NRMF, _c2013.
300			_a36 pages: _billustrations, tables, photos; _c28 cm.
336			_atext _2rdacontent
337			_aunmediated _2rdamedia
338			_avolume _2rdacarrier
504			_aIncludes appendices and bibliographical references.
520			_aAbstract: Free radicals are constantly generated and may cause extensive damage to tissues and biomolecules leading to various ill conditions, especially degenerative diseases, and extensive lysis of cells. Many synthetic drugs protect against oxidative damage but have adverse side effects. An alternative solution to the problem is consuming natural antioxidants from supplements and also traditional medicine. Examples of these are Jasminum sambac and Cananga odorata. These were known as folklore medicine for centuries and no local paper has established their biochemical properties. Antioxidant screening was done by preparing crude methanolic extracts of the J. sambac and C. odorata leaves and ascorbic acid, which were subjected to DPPH scavenging assay using a series of dilutions and run into a spectrophotometer at 505 nm. At the highest concentration of 250µg/ml., J. sambac and C. odorata methanolic crude leaf extracts each have a %Inhibition of 71.97% and 77.78% respectively, while the positive control (ascorbic acid) has a %Inhibition of 94.40%. Based on the Student T-test statistical analysis of the %Inhibition obtained, both samples showed that antioxidant property and capacity of the crude leaf extracts were statistically comparable (p >0.05) with ascorbic acid. The IC50 for both crude leaf extracts of J. sambac and C. odorata of 156.40 and 106.18 µg/mL respectively, were higher than that of ascorbic acid.
521			_aTHDBN
700			_aSection 1-A2 _eauthor
700			_aAlcantara, Hena, MD. _eadviser
942			_2lcc _cRU