000			03550nam a22005057a 4500
999			_c8675 _d8675
001			M CFM ND 0002
003			PILC
005			20240720152652.0
008			160505b xxu||||| |||| 00| 0 eng dND
040			_beng _cFEU-NRMF MEDICAL LIBRARY _erda
041			_aenglish
050			_aM CFM ND 0002
245			_aA Comparative study on the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of isoniazid (INH) by international, multinational, and local drug companies / _cJhoanna O. Delos Reyes, Aileen Rodora M. Abueg, Eric Emil M. Acosta, Aldrin A. Aldaba, Rhea Maureen S. Angeles, Zarina R. Balagtas, Ma. Rema C. Bello, James Dennis M. Bobis, Jerome Bolivar, Noriel L. Buenavente, Jeanette A. Catapang, Cherry Veil G. Cabisudo, Raymond Felix M. Collao, Jaybemi Comia, Cherry Y. Cortez, Marigil J. Dofiles, Allan A. Evangelista, Arnaldo L. Evangelista, Maryliza P. Evangelista, Flordeliza S.A. Fernando, Irene L. Gardiner and Tzy-Guei Hu.
260			_aFairview, Quezon City: _bDepartment of Community and Family Medicine, FEU-NRMF.
300			_billusrations, tables, photos; _c28 cm.
336			_atext _2rdacontent
337			_aunmediated _2rdamedia
338			_avolume _2rdacarrier
504			_aIncludes appendices and bibliographical references.
520			_aAbstract: The Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of Isoniazid manufactured by different Drug Companies were determined and investigated Six INH tablets were randomly chosen from the 4 selected Drug companies and were subjected to anti-microbial effectiveness testing in vitro using Broth Dilution Method. Results were analyzed using ANOVA and their cost-effectiveness were ascertained by comparing their unit price in relation to their bacteriostatic and bactericidal activity. It was found out that there was a significant difference in the antimicrobial effectiveness of the INH tablets from the selected Drug Companies. It was apparent that INH from Drug Company A, a multi-national drug companyy, exhibited the lowest concentration to inhibit tubercle bacilli growth as well as the lowest concentration to effectiively kill the tubercle colonies in the subcultures from non-turbid tubes. These INH tablets cost much more compared to the locally produced Isoniazid. However, the fact that its anti-microbial effectiveness is superior in comparison to the other INH tablets from the other Drug Companies it can be implied that it has the greatest advantage.
521			_aTHDCFM
700			_aDelos Reyes, Jhoanna O. _eauthor
700			_aAbueg, Aileen Rodora M. _eauthor
700			_aAcosta, Eric Emil M. _eauthor
700			_aAldaba, Aldrin A. _eauthor
700			_aAngeles, Rhea Maureen S. _eauthor
700			_aBalagtas, Zarina R. _eauthor
700			_aBello, Ma. Rema C. _eauthor
700			_aBobis, James Dennis M. _eauthor
700			_aBolivar, Jerome _eauthor
700			_aBuenavente, Noriel L. _eauthor
700			_aCatapang, Jeanette A. _eauthor
700			_aCabisudo, Cherry Veil G. _eauthor
700			_aCollao, Raymond Felix M. _eauthor
700			_aComia, Jaybemi _eauthor
700			_aCortez, Cherry Y. _eauthor
700			_aDofiles, Marigil J. _eauthor
700			_aEvangelista, Allan A. _eauthor
700			_aEvangelista, Arnaldo L. _eauthor
700			_aEvangelista, Maryliza P. _eauthor
700			_aFernando, Flordeliza S.A. _eauthor
700			_aGardiner, Irene L. _eauthor
700			_aHu, Tzy-Guei _eauthor
942			_2lcc _cRU