000			03429nam a22004817a 4500
999			_c8708 _d8708
001			M CFM 1993 0001
003			PILC
005			20240720152658.0
008			160505b1993 xxu||||| |||| 00| 0 eng d
040			_beng _cFEU-NRMF MEDICAL LIBRARY _erda
041			_aenglish
050			_aM CFM 1993 0001
245			_aAntimicrobial effect of the crude methanol extracts of three marine sponges from Bolinao, Pangasinan on selected pathogens using agar diffusion method (August-September, 1993) / _cRowena P. Cardenas, Cristina U. Chua, Rachelle U. Chua, Lorichelle B. Dela Cruz, Niel Andrew S.J. De Lumen, Gladys S. Demdam, Ann Veronique C. Eguaras, Katherine T. Gabon, Anthony G. Jao , Ann Rizza B. Justimbaste, Raquel B. Laylo, Glenn M. Luzano, Zarah S. Malo, Fe F. Mangalindan, Jeanne U. Ngo, Gjay L. Ordinal, Cherry C. Padilla, Claudette P. Ricero, Stella Marie S. Rondilla and Joselito R. Yulo.
260			_aManila: _bDepartment of Community and Family Medicine, FEU-NRMF, _c1993.
300			_a49 pages: _billustrations, tables, photos; _c28 cm.
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
504			_aIncludes appendices and bibliographical references.
520			_aAbstract: The oceans are a largely entapped reservoir for interesting, unusual and potentially useful natural pharmaceutical products (fox, 1982). The potentials of our local marine sponges as a source of drugs or as models for the synthesis of isolated and identified active compounds show promising results. It is then the objective of this in vitro study to determine the antimicrobial activity of the crusade methanol extract of three unknown marine sponges coded : S28, S50 S50A from Bolinao, Pangasinan on selected pathogens : E. coli, S. typhi, P. aeruginosa, P. mirabilis, Enterobacter sp. using Agar Diffusion Method by measuring their zones of inhibitions and comparing them to those exhibited by known antibiotics : Chloramphenicol for S. typhi and Norfloxacin for the rest of the organisms. Results revealed that all three sponge extracts exhibited significant antimicrobial activity against S. typhi and P. aeruginosa, two extracts (S50 and S50A) against P. mirabilis, and S28 against Enterobacter sp. Growth of E. coli was not at all arrested by any of the sponges, This suggest that the aforementioned sponges can be at par with our known antibiotics should further studies be pursued requiring isolation and characterization of each identifiable active compound.
521			_aTHDCFM
700			_aCardenas, Rowena P. _eauthor
700			_aChua, Cristina U. _eauthor
700			_aChua, Rachelle U. _eauthor
700			_aDela Cruz, Lorichelle B. _eauthor
700			_aDe Lumen, Neil Andrew S.J. _eauthor
700			_aDemdam, Gladys S. _eauthor
700			_aEguaras, Ann Veronique C. _eauthor
700			_aGabon, Katherine T. _eauthor
700			_aJao, Anthony G. _eauthor
700			_aJustimbaste, Ana Rizza B. _eauthor
700			_aLaylo, Raquel B. _eauthor
700			_aLuzano, Glenn M. _eauthor
700			_aMalo, Zarah S. _eauthor
700			_aMangalindan, Fe F _eauthor
700			_aNgo, Jeanne U _dauthor
700			_aOrdinal, Gjay L _eauthor
700			_aPadilla, Cherry C _eauthor
700			_aRicero, Claudette P _eauthor
700			_aRondilla, Stella Marie S _eauthor
700			_aYulo, Joselito R. _eauthor
942			_2lcc _cRU