000 02010nam a22002537a 4500
999 _c8940
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005 20240720152728.0
008 160505b1999 xxu||||| |||| 00| 0 eng d
040 _cFEU-NRMF MEDICAL LIBRARY
050 _aMPHAR19990005
245 _aCOMPARATIVE STUDY OF THE ANTI-INFLAMMATORY EFFECT OF MORINGA OLEIFERA SEED EXTRACT (MALUNGGAY) WITH THE STANDARD DRUG, ASPIRIN
260 _aQUEZON CITY
_bFEU-NRMF
_c1999
520 _aABSTRACT: The anti-inflammatory property of Moringa oleifera seed extract (Malunggay) and aspirin was compared in this study. This is to determine the effectivity with the seed extract as well as its effective dose in reducing the inflammation induced by 1% carrageenan. A total of 25 swiss mice were then subjected to the experimentation proper that of which 5 mice served as the (-) control (NSS), 10 mice as the (+) control (ASA) and another 10 mice as the extract group respectively. Inflammation of the paw was induced by injection of 1% carrageenan. Its measurement in each group served as our basis of results. It was found out that Moringa oleifera (Malunggay) seed extract significantly reduced inflammation by 0.0443mL as compared with Aspirin which reduced inflammation by 0.0366 ml. As computed in the statistical analysis using t-test, we can say that Moringa oleifera (Malungay) seed extract is comparable to Aspirin as an anti inflammatory agent with a -0.0077 difference. If further studies would be done, it is suggested that larger animals be used instead of mice, that a standard plethysmometer be used, and the adverse effects and component of Malunggay responsible for its anti-inflammatory effect be studied as well.
521 _afarmakoloji
700 _aBacani, Jemalia M.
700 _aAguilar, Donato A.
700 _aBatara, Liezl M.
700 _aCastillo, Donna J.
700 _aCastro, Ma. Teresa L.
700 _aCelebre, Fedeliza F.
700 _aCereno, Monica G.
700 _aChan, Nikki Carla G.
942 _2lcc
_cTH