000			02131nam a22002897a 4500
999			_c8999 _d8999
003			PILC
005			20240720152733.0
008			160505b2003 xxu||||| |||| 00| 0 eng d
040			_cFEU-NRMF MEDICAL LIBRARY
041			_aEnglish
050			_aMPHAR20030004
245			_aA COMPARATIVE STUDY ON THE TRIGLYCERIDE LOWERING EFFECT OF GEMFIBROZIL AND FENOFIBRATE.
260			_aQuezon City _bFEU-NRMF _cMarch 2003
300			_a22 pages
520			_aABSTRACT: The effectivity of Gemfibrozil and Fenofibrate was compared using serum triglyceride levels 24 of mature male rabbits as a parameter. Initially triglyceride levels of the subjects were elevated by administration of epinephrine. Paired data analysis showed that 10 days induction of epinephrine can cause significant elevation of triglyceride levels. The rabbits were then randomly assigned into three groups. Group A was the control while groups B and C were the treatment groups that received 150mg/kgBW/day gemfibrozil and 40mg/kgBW/day Fenofibrate respectively. Two-sample t-test was used to compare serum triglyceride levels of rabbits after induction of epinephrine (AIE) and after treatment (AT) within the groups mentioned. All showed significant lowering after treatment. This implies that one-week removal of epinephrine and administration of treatment drugs is enough to show significant lowering in triglyceride levels of rabbits. Comparing the mean absolute differences of triglyceride levels after induction of epinephrine and after treatment between groups B and C showed that the group treated with Gemfibrozil had lower triglyceride level. However, two-sample t-test with t value of 2.306 showed that this difference is not significant.
521			_afarmakoloji
700			_aAgustin, Avelino Jr.
700			_aCommandante, Christian
700			_aElepano, Ronaldo III
700			_aJaropillo, Wilfredo
700			_aJavier, Maria Yvette
700			_aLangcauon, Sheryll
700			_aLucas, Mary Grace
700			_aRamirez, Marie Abigail
700			_aVillavicencio, Charity
942			_2lcc _cTH