000			02922nam a22003137a 4500
999			_c9728 _d9728
001			M BIO 2014 0002
003			PILC
005			20240720152846.0
008			170217b xxu||||| |||| 00| 0 eng d
040			_beng _cFEU-NRMF MEDICAL LIBRARY _erda
041			_aenglish
050			_aM BIO 2014 0002
245			_aPrevalence of zinc deficiency and its relationship with glycosylated hemoglobin levels among type II diabetes mellitus patients / _cSection B; Mari-Ann B. Bringas; Dolores V. Viiran.
260			_aFairview, Quezon City: _bDepartment of Biochemistry, FEU-NRMF, _c2014.
300			_a33 pages: _billustrations, tables; _c28 cm.
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
504			_aIncludes appendices and bibliographical references.
520			_aAbstract: Diabetes mellitus is a chronic disease considered as a global problem. Decreased zinc (Zn) levels, which affects the ability of the islet cell to produce and secrete insulin, might compound the problem associated with type 2 diabetes. Zinc promotes different biochemical reactions in the body and is being investigated to aide in the improvement of management strategies for various diseases such as DM. To determine the prevalence of zinc deficiency and to correlate serum Zn with HbA1c levels of Type II Diabetic patients. Serum Zinc and HbA1c levels were determined on blood samples from 101 patients in FEU-NRMF and VMMC. General information was acquired via interview and anthropometric assessment was also conducted. Zinc deficiency was summarized using percentages or proportion. Serum zinc and glycosylated hemoglobin levels (HbA1c) were summarized using mean and standard deviation. Linear regression, T-test, ROC characterization and Chi-square was utilized to correlate serum zinc levels with HbA1c. Level of significance was set at ɑ= 0.05 The prevalence of ZD in the sample population was 5.9%. Linear Regression (F=0.6853 > ɑ = 0.05) showed negative correlation between HbA1c and Zn levels. T-test revealed no significant difference between Zn levels of controlled and uncontrolled DM (P=value = 0.645,> ɑ = 0.05). ROC obtained cut off serum zinc levels 70 µg/dl or higher predicted good control of DM, although statistically in significant (p > ɑ = 0.05). Prevalence of ZD was low among T2DM patients. However, there was occurrence of more uncontrolled DM than controlled DM among patients with ZD. Inverse relationship was observed between serum Zn levels and HbA1c levels. Normal to high Zinc levels > 70 µg/dL predicted good control of Zinc levels. The trend however, is statistically insignificant.
521			_aTHDBN
650			_aprevalence
650			_azinc deficiency
650			_adiabetes
700			_aSection B _eauthor
700			_aBringas, Mari-Ann B., MD. _eadviser
700			_aViiran, Dolores V., MD. _eadviser
942			_2lcc _cRU