Association of hemoglobin a1c levelswith adverse perinatal outcomes amongwomen with gestational diabetes mellitus / Jazztine A. Rosales and Lylah D. Reyes.

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Language: english Publication details: Fairview, Quezon City: Department of Obstetrics and Gynecology, FEU-NRMF, 2019.Description: 44 pages: tables; (in folder) with flash drive (soft copy)Content type:

text

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unmediated

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volume

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LOC classification:

OB 2019 0004

Summary: Abstract: Gestational diabetes mellitus (GDM) is a common medical complication of pregnancy. A favorable blood glucose control is essential toensure good perinatal outcome. Based on literatures, HbA1C is reflective of maternal glycemic control and can be used to monitor not just blood glucose levels but perinatal outcomes as well. To determine the association of HbA1C levels with adverse perinatal outcomes among patients with GDM in the outpatient section of a tertiary hospital. Included were 130 participants with GDM aged 18 to 35 years old. The HbA1c levels during the first testing (23 to 25 weeks) ranged from 3.9 to 7.6% while second testing (35 to 37 weeks) ranged from 3.8 to 6.9%. In the second testing 33.85% of women remained to have a higher HbA1c levels. As age increases, HbA1c was significantly higher (25.34.8 vs 29.74.5, p <0.001). Likewise, the higher the gravidity (1.50.75 vs 1.970.99, p 0.0013) and parity (0.38 0.64 vs 0.730.93, p 0.005), HbA1c level was also higher. Majority had good perinatal outcomes but those with adverse outcomes had higher HbA1c (8.3% vs 30.4%, p 0.04) . Most neonates have good APGAR score, while those neonates with poor score were delivered by mothers with higher HbA1c values. (0 vs 10.9%, p 0.002). Most neonates had birthweights appropriate for gestational age. But those neonates that are large for gestation were born to mothers with higher HbA1c values (0 vs 8.7%, p <0.001). The higher the HbA1c levels, even within the non-diabetic range, are associated with increased risk of adverse perinatal outcome among GDM patients. This suggests that HbA1c could be recommended as a part of the comprehensive care of pregnant women with GDM and can be used to identify those GDM patients who would need close monitoring.

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Holdings
Item type	Current library	Call number	Status	Notes	Date due	Barcode
Room Use	Far Eastern University - Nicanor Reyes Medical Foundation Research	OB 2019 0004 (Browse shelf(Opens below))	Available	with flash drive (soft copy)		R000955

Includes appendices and bibliographical references.

Abstract: Gestational diabetes mellitus (GDM) is a common medical complication of pregnancy. A favorable blood glucose control is essential toensure good perinatal outcome. Based on literatures, HbA1C is reflective of maternal glycemic control and can be used to monitor not just blood glucose levels but perinatal outcomes as well. To determine the association of HbA1C levels with adverse perinatal outcomes among patients with GDM in the outpatient section of a tertiary hospital. Included were 130 participants with GDM aged 18 to 35 years old. The HbA1c levels during the first testing (23 to 25 weeks) ranged from 3.9 to 7.6% while second testing (35 to 37 weeks) ranged from 3.8 to 6.9%. In the second testing 33.85% of women remained to have a higher HbA1c levels. As age increases, HbA1c was significantly higher (25.34.8 vs 29.74.5, p <0.001). Likewise, the higher the gravidity (1.50.75 vs 1.970.99, p 0.0013) and parity (0.38 0.64 vs 0.730.93, p 0.005), HbA1c level was also higher. Majority had good perinatal outcomes but those with adverse outcomes had higher HbA1c (8.3% vs 30.4%, p 0.04) . Most neonates have good APGAR score, while those neonates with poor score were delivered by mothers with higher HbA1c values. (0 vs 10.9%, p 0.002). Most neonates had birthweights appropriate for gestational age. But those neonates that are large for gestation were born to mothers with higher HbA1c values (0 vs 8.7%, p <0.001). The higher the HbA1c levels, even within the non-diabetic range, are associated with increased risk of adverse perinatal outcome among GDM patients. This suggests that HbA1c could be recommended as a part of the comprehensive care of pregnant women with GDM and can be used to identify those GDM patients who would need close monitoring.

Research - Department of Obstetrics & Gynecology

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