A Comparative study on the effects of carbonyl iron and ferrous sulfate in the prevention of iron deficiency anemia among high-risk pregnant women seen at the out-patient department of a tertiary medical center in 2019 to 2020 / [principal investigator]: Lim, Ivy Grace C. [co-author]: Reyes, Lylah D.

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Language: English Publication details: Fairview, Quezon City: Department of Obstetrics & Gynecology, FEU-NRMF, 2023Description: (in folder) with flash drive (soft copy)Content type:

text

Media type:

unmediated

Carrier type:

volume

LOC classification:

OB 2023 0002

Summary: ABSTRACT: Background: Iron Deficiency Anemia (IDA), one of global health concerns among pregnant women, contributes to maternal and fetal morbidity and mortality rates. Ferrous Sulfate, a widely prescribed oral iron supplement for prevention and treatment of Iron Deficiency Anemia, has gastrointestinal side effects that affect patient-compliance. Carbonyl Iron has been reported to have less adverse effects but there are limited studies comparing its effects and adverse outcomes with Ferrous Sulfate. Objective: Compare the effect of Carbonyl Iron and Ferrous Sulfate in the prevention of Iron Deficiency Anemia among high-risk pregnant women seen at the Out Patient Department of a tertiary medical center. Methods: This is a retrospective cohort study that reviewed medical records of 415 eligible pregnant women aged 18 to 40 years old seen at the outpatient department of a tertiary medical center from 2019 to 2020 after purposive sampling. Gathered data were encoded using Microsoft Excel and analyzed using intercooled strata version 9.1. Results: Of the 415 eligible medical records reviewed, 50.84% (211) took Ferrous Sulfate and 49.16% (204) were given Carbonyl Iron. There was no significant difference in preventing Iron Deficiency Anemia (p = 0.894) between the two oral iron supplement. Adverse effects such as Nausea (p= 0.962), vomiting (p = 0.894, diarrhea (p= 0.490), constipation (p = 0.326) and gastrointestinal upset (p=0.688) were also comparable. Conclusion: Ferrous sulfate and Carbonyl iron are both comparable in preventing iron deficiency anemia with similar adverse effect profile. Carbonyl iron may be used alternatively among high risk pregnant women within similar or lower price range. Keywords: Ferrous Sulfate, Carbonyl Iron, Iron Deficiency Anemia, Prevention, Adverse Effects

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Item type	Current library	Call number	Status	Date due	Barcode
Room Use	Far Eastern University - Nicanor Reyes Medical Foundation	OB 2023 0002 (Browse shelf(Opens below))	Available		R000714

Includes bibliographical references

ABSTRACT:

Background: Iron Deficiency Anemia (IDA), one of global health concerns among pregnant women, contributes to maternal and fetal morbidity and mortality rates. Ferrous Sulfate, a widely prescribed oral iron supplement for prevention and treatment of Iron Deficiency Anemia, has gastrointestinal side effects that affect patient-compliance. Carbonyl Iron has been reported to
have less adverse effects but there are limited studies comparing its effects and adverse outcomes with Ferrous Sulfate.

Objective: Compare the effect of Carbonyl Iron and Ferrous Sulfate in the prevention of Iron Deficiency Anemia among high-risk pregnant women seen at the Out Patient Department of a tertiary medical center.

Methods: This is a retrospective cohort study that reviewed medical records of 415 eligible pregnant women aged 18 to 40 years old seen at the outpatient department of a tertiary medical center from 2019 to 2020 after purposive sampling. Gathered data were encoded using Microsoft Excel and analyzed using intercooled strata version 9.1.
Results: Of the 415 eligible medical records reviewed, 50.84% (211) took Ferrous Sulfate and
49.16% (204) were given Carbonyl Iron. There was no significant difference in preventing Iron
Deficiency Anemia (p = 0.894) between the two oral iron supplement. Adverse effects such as
Nausea (p= 0.962), vomiting (p = 0.894, diarrhea (p= 0.490), constipation (p = 0.326) and gastrointestinal upset (p=0.688) were also comparable.

Conclusion: Ferrous sulfate and Carbonyl iron are both comparable in preventing iron
deficiency anemia with similar adverse effect profile. Carbonyl iron may be used alternatively
among high risk pregnant women within similar or lower price range.

Keywords: Ferrous Sulfate, Carbonyl Iron, Iron Deficiency Anemia, Prevention, Adverse
Effects

Research - Department of Obstetrics & Gynecology

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