The Association of maternal and neonatal risk factors with early onset neonatal sepsis among term neonates / Pamela S. Peralta-Pongco.

Abstract: To determine the association of maternal and neonatal risk factors with early onset neonates in FEU-NRMF Medical Center Neonatal Intensive Care Unit for 2011-2012. A retrospective review of all charts with the initial diagnosis of T/C Neonatal Sepsis in FEU-NRMF Medical Center Neonatal Intensive Care Unit Charts of term, appropriate for gestational age neonates with the initial diagnosis of T/C Neonatal Sepsis based on maternal and neonatal risk factors admitted at Neonatal Intensive Care Unit during 2011-2012. From 377 patients, only 165 (43.8%) were diagnosed with early on set neonatal sepsis based on clinical manifestations and or blood culture positive. For the maternal risk factors, only presence of UTI was found to have an association with detection of sepsis given p-value less than 0.05 and among the neonatal risk factors; Respiratory distress, meconium stained, vomiting and poor suck appeared to have significant relationship with presence of sepsis among neonates having p-values less than 0.05. The odds presented in the maternal risk factors are lower than the odds for the neonatal factors. This implies that neonatal factors may have greater impact for the detection of sepsis of a newborn. Neonatal risk factors such as respiratory distress, vomiting, poor suck and mecomiun staining has strongest possibility of developing early onset neonatal sepsis compared to the maternal risk factors.

Research - Department of Child Health