A Comparative study between lissamine green and fluorescein dye using National Eye Institute (NEI) grading classification in diagnosing dry eye syndrome / Lord Ryan L. Lopez, Angelico L. Alejo and Ma. Donna D. Santiago.

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Language: english Publication details: Fairview, Quezon City: Department of ORL-HNS (ENT), FEU-NRMF, 2012.Description: illustrations, tables; (in folder)Content type:

text

Media type:

unmediated

Carrier type:

volume

LOC classification:

ENT 2012 0003

Summary: Abstract: Majority of the journals published still consider. fluorescein dye as the gold standard for diagnosing dry eye syndrome. A recently published seminal dry eye workshop proceedings defined Lissamine green, an organic dye, as a gold standard for demonstrating ocular surface staining. The purpose of this study is to determine if there is a significant difference between lissamine green and fluorescein dye with the use of the conjunctival NEI grading classification for devitalized tissue in determining the severity of dry eye syndrome by the comparison of objective staining scores. All patients, 50-70 years old, suspected of having a dry eye syndrome underwent general ophthalmologic examination including tear break-up tine and tear meniscus test. Patients were also screened using the Schein questionair. Eighty-eight patients diagnosed with dry eye syndrome were included in the study. Lissamine green strip and fluorescein dye strip were instilled into lower palpebral conjunctiva. One eye was instilled with fluorescein dye and the other eye with Lissamine green. The bulbar conjunctival patterns were documented on each eye and graded using the conjuctival NEI grading clissification for devitalized tissue in dry eye syndrome. Statistical analysis (t-test) were applied to determine if there is a significant difference on conjunctival NEi grading clissification for devitalized tissue in dry eye syndrome between the two dyes. Results showed that there was nosignificant difference in terms of giagnosing the severity of dry eye syndrome with the use of fluorescein dye and Lissamine green. With the use of either Lissamine green of fluorescein dye, we can diagnose dry eye syndrome. We can use the said dyes interchangeably to diagnose the severity of dry eye syndrome and give its appropriate treatment.

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Item type	Current library	Call number	Status	Notes	Date due	Barcode
Research	Far Eastern University - Nicanor Reyes Medical Foundation Research	ENT 2012 0003 (Browse shelf(Opens below))	Not For Loan	draft		R000708
Room Use	Far Eastern University - Nicanor Reyes Medical Foundation Research	ENT 2012 0003 (Browse shelf(Opens below))	Available			R000440

Includes appendices and bibliographical references.

Abstract: Majority of the journals published still consider. fluorescein dye as the gold standard for diagnosing dry eye syndrome. A recently published seminal dry eye workshop proceedings defined Lissamine green, an organic dye, as a gold standard for demonstrating ocular surface staining. The purpose of this study is to determine if there is a significant difference between lissamine green and fluorescein dye with the use of the conjunctival NEI grading classification for devitalized tissue in determining the severity of dry eye syndrome by the comparison of objective staining scores. All patients, 50-70 years old, suspected of having a dry eye syndrome underwent general ophthalmologic examination including tear break-up tine and tear meniscus test. Patients were also screened using the Schein questionair. Eighty-eight patients diagnosed with dry eye syndrome were included in the study. Lissamine green strip and fluorescein dye strip were instilled into lower palpebral conjunctiva. One eye was instilled with fluorescein dye and the other eye with Lissamine green. The bulbar conjunctival patterns were documented on each eye and graded using the conjuctival NEI grading clissification for devitalized tissue in dry eye syndrome. Statistical analysis (t-test) were applied to determine if there is a significant difference on conjunctival NEi grading clissification for devitalized tissue in dry eye syndrome between the two dyes. Results showed that there was nosignificant difference in terms of giagnosing the severity of dry eye syndrome with the use of fluorescein dye and Lissamine green. With the use of either Lissamine green of fluorescein dye, we can diagnose dry eye syndrome. We can use the said dyes interchangeably to diagnose the severity of dry eye syndrome and give its appropriate treatment.

Research - Department of Otolaryngology

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