Patient and physician factors affecting the transfusion practices for cases of upper gastrointestinal bleeding admitted at FEU-NRMF Medical Center : a cross-sectional study / Henry C. Valerio

Includes appendices and bibliographical references.

ABSTRACT: Acute upper gastrointestinal bleeding (UGIB) is a common emergency condition associated with high morbidity and mortality. It is a frequent indication for red-cell transfusion because acute blood loss can decrease tissue perfusion and the delivery of oxygen to tissues. Transfusion may be lifesaving in patients with massive exsanguinating bleeding. However, in most cases hemorrhage is not so severe, and in such circumstances the safest and most effective transfusion strategy is controversial therfore, the optimal hemoglobin threshold at which to transfuse is unclear. Two observational studies have indicated an association between RBC transfusion after UGIB and risk of further bleeding and mortality. A recently published randomised trial foundthat liberal approach to transfusion led to an increased risk of mortality

Research - Department of Pathology & Laboratory Diagnosis