Catastrophic antiphospholipid antibody syndrome in a 36-year old female with systemic lupus erythematosus /
De Leon, Maria Frances Noreen C., MD.
Catastrophic antiphospholipid antibody syndrome in a 36-year old female with systemic lupus erythematosus / Maria Frances Noreen C. De Leon. - Fairview, Quezon City Department of Internal Medicine, FEU-NRMF, 2018 - photos (black and white); (in folder)
Includes bibliographical references.
ABSTRACT: Antiphospholipid syndrome (APS) is a multisystem autoimmune condition characterized by vascular thromboses and/or pregnancy loss associated with persistently positive antiphospholipid antibodies (aPL). Catastrophic APS (CAPS) is the most severe form of APS with multiple organ involvement developing over a short period of time, usually associated with microthromnosis. This is a case of a 36-year old female with history of 2 pregnancy losses, admitted due to right upper quadrant pain and subsequently developed multisytemic organ failure. Patient presented with cerebrovascular infract, pleural effusion, renal failure, heart failure, and psychosis with positive titers for lupus anticoagulant and ANA. Refractory to pulse therapy and anticoagulation, rituximab regimen was then initiated which showed significant improvement in patient's condition.
Research - Department of Medicine
MED20180005
Catastrophic antiphospholipid antibody syndrome in a 36-year old female with systemic lupus erythematosus / Maria Frances Noreen C. De Leon. - Fairview, Quezon City Department of Internal Medicine, FEU-NRMF, 2018 - photos (black and white); (in folder)
Includes bibliographical references.
ABSTRACT: Antiphospholipid syndrome (APS) is a multisystem autoimmune condition characterized by vascular thromboses and/or pregnancy loss associated with persistently positive antiphospholipid antibodies (aPL). Catastrophic APS (CAPS) is the most severe form of APS with multiple organ involvement developing over a short period of time, usually associated with microthromnosis. This is a case of a 36-year old female with history of 2 pregnancy losses, admitted due to right upper quadrant pain and subsequently developed multisytemic organ failure. Patient presented with cerebrovascular infract, pleural effusion, renal failure, heart failure, and psychosis with positive titers for lupus anticoagulant and ANA. Refractory to pulse therapy and anticoagulation, rituximab regimen was then initiated which showed significant improvement in patient's condition.
Research - Department of Medicine
MED20180005
