Comparative evaluation of the effects of Ketamine and Fentanyl on recovery of cognitive function and memory in patients undergoing colonoscopy /

Comparative evaluation of the effects of Ketamine and Fentanyl on recovery of cognitive function and memory in patients undergoing colonoscopy / April Joy Janice J. Amata and Ernest M. Dela Cerna Jr. - Fairview, Quezon City: Department of Anesthesiology, FEU-NRMF, 2019. - 26 pages: illustrations, tables; (in folder) with CD (soft copy).

Includes appendices and bibliographical references.

Abstract: The popularity of endoscopic procedures for diagnosis and therapy has increased with the aid of sedation for purposes of anxiolysis and prevention of complications secondary to intraprocedure sympathetic activation. The belief that any form of sedation leads to impaired memory and cognition has been a subject of debate for years. In this regard, the primary purpose of this investigation is to evaluate the postprocedure function of patients in terms of recovery of cognition and memory with two sedation regimens used in the outpatient setting of gastroscopic procedures, specifically, colonoscopy. A convenience sample of 137 subjects was randomly assigned. Cognition and memory was assessed using the GPCOG screening and MIS test on the second hour after cessation of drug administration. The results of this investigation indicate that there is no significant difference in the recovery rate of cognition and memory between the two groups.

Research - Department of Anesthesiology


colonoscopy
conscious sedation
Propofol-Ketamine
Propofol-Fentanyl
postprocedure cognitive impairment

ANES 2019 0002