Association of factors with the use of oxytocin combined with other uterotonics versus oxytocin alone in the prevention of primary postpartum hemorrhage in a tertiary medical center from 2016 to 2019. / [principal investigator]: Dosado, Odessa L. [co-author]: Reyes, Lylah D.
Association of factors with the use of oxytocin combined with other uterotonics versus oxytocin alone in the prevention of primary postpartum hemorrhage in a tertiary medical center from 2016 to 2019. / [principal investigator]: Dosado, Odessa L. [co-author]: Reyes, Lylah D.
- fairview, Quezon City: Department of OBgyne, FEU-NRMF, 2023
- (in folder) with flash drive (soft copy)
Includes bibliographical refernces.
ABSTRACT
Background: Active Management of Third Stage of Labor (AMTSL), includes prompt administration of uterotonic agents after delivery with oxytocin as first line agent to prevent uterine atony. However, there is an increasing trend with use of combination uterotonics for prevention of uterine atony even among low risk women.
Objective: Determine the association of factors with the use of oxytocin combined with other uterotonics and oxytocin alone in prevention of primary postpartum hemorrhage in a tertiary medical center from 2016 to 2019
Methods: A four-year cross-sectional study which reviewed charts of women who delivered and were given single or combination uterotonics postpartum. Purposive sampling done. Analysis conducted separately for vaginal delivery and cesarean section. Data extracted included maternal- and obstetric-related factors, as well as uterotonic used and its adverse effects.
Result: There were 450 charts of women with singleton pregnancies reviewed, 58.2% (262) had vaginal delivery while 41.7% (188) delivered by cesarean section. Combined uterotonics given to 42.4% (192) of cases, mostly among cesarean deliveries at 82.3% (158/192). Vaginal delivery cases with combined uterotonics showed significantly lower proportion of women with normal preoperative hematocrit (p 0.01). While for cesarean section, use of combined uterotonics was significantly higher among women with blood loss > 500 mL. No adverse effects and history of postpartum hemorrhage recorded.
Conclusion: Combined uterotonics was commonly used for cesarean delivery. Factors associated the use of combined uterotonics in prevention of postpartum hemorrhage includes greater estimated blood loss and normal pre- operative hematocrit.
Keywords: Uterotonics, Combination uterotonics, Oxytocin, Uterine atony, Postpartum hemorrhage.
Department of Obstetrics & Gynecology Research - Department of Obstetrics & Gynecology
OB 2023 0004
Includes bibliographical refernces.
ABSTRACT
Background: Active Management of Third Stage of Labor (AMTSL), includes prompt administration of uterotonic agents after delivery with oxytocin as first line agent to prevent uterine atony. However, there is an increasing trend with use of combination uterotonics for prevention of uterine atony even among low risk women.
Objective: Determine the association of factors with the use of oxytocin combined with other uterotonics and oxytocin alone in prevention of primary postpartum hemorrhage in a tertiary medical center from 2016 to 2019
Methods: A four-year cross-sectional study which reviewed charts of women who delivered and were given single or combination uterotonics postpartum. Purposive sampling done. Analysis conducted separately for vaginal delivery and cesarean section. Data extracted included maternal- and obstetric-related factors, as well as uterotonic used and its adverse effects.
Result: There were 450 charts of women with singleton pregnancies reviewed, 58.2% (262) had vaginal delivery while 41.7% (188) delivered by cesarean section. Combined uterotonics given to 42.4% (192) of cases, mostly among cesarean deliveries at 82.3% (158/192). Vaginal delivery cases with combined uterotonics showed significantly lower proportion of women with normal preoperative hematocrit (p 0.01). While for cesarean section, use of combined uterotonics was significantly higher among women with blood loss > 500 mL. No adverse effects and history of postpartum hemorrhage recorded.
Conclusion: Combined uterotonics was commonly used for cesarean delivery. Factors associated the use of combined uterotonics in prevention of postpartum hemorrhage includes greater estimated blood loss and normal pre- operative hematocrit.
Keywords: Uterotonics, Combination uterotonics, Oxytocin, Uterine atony, Postpartum hemorrhage.
Department of Obstetrics & Gynecology Research - Department of Obstetrics & Gynecology
OB 2023 0004
