Hypothermia as neuroprotectant during acute ischemic stroke: a meta-analysis / [principal investigator]: Roxas, Gina Marie M.
Hypothermia as neuroprotectant during acute ischemic stroke: a meta-analysis / [principal investigator]: Roxas, Gina Marie M.
- Fairview, Quezon City: Department of Internal Medicine, FEU-NRMF, 2023
- ( in folder ) with flash drive (soft copy)
Includes bibliographical references.
ABSTRACT:
Acute ischemic stroke is considered the leading cause of disability worldwide and the 3rd leading cause of death, its neurological outcome is secondary to vascular occlusions which leads to brain tissue ischemia. It is known that infarct progress in a circumferential fashion towards its maximum volume over 7 hours. This study aims to explain the effect of maintaining hypothermia during acute ischemic stroke. There is a noted decrease in the cerebral metabolic rate by 7-10%for every degree Celsius reduction in body temperature which explain the improvement of the NIHSS score among patient maintained with a core body temperature of 32-35 degrees as shown in the results with a p value of less than 0.05 compared to patient maintained on core body temperature. Improvement upon follow-up was seen by using MRS scoring, there is noted significant association
between hypothermia and a lower level of MRS.
Department of Medicine Research - Department of Medicine
MED 2023 0007
Includes bibliographical references.
ABSTRACT:
Acute ischemic stroke is considered the leading cause of disability worldwide and the 3rd leading cause of death, its neurological outcome is secondary to vascular occlusions which leads to brain tissue ischemia. It is known that infarct progress in a circumferential fashion towards its maximum volume over 7 hours. This study aims to explain the effect of maintaining hypothermia during acute ischemic stroke. There is a noted decrease in the cerebral metabolic rate by 7-10%for every degree Celsius reduction in body temperature which explain the improvement of the NIHSS score among patient maintained with a core body temperature of 32-35 degrees as shown in the results with a p value of less than 0.05 compared to patient maintained on core body temperature. Improvement upon follow-up was seen by using MRS scoring, there is noted significant association
between hypothermia and a lower level of MRS.
Department of Medicine Research - Department of Medicine
MED 2023 0007
